TNZ

The first part was divided into 5 teams, each team was breathed TNZ solution of 100mg/ kg weight into stomach in 5 days continuously.

第一批60只KM小鼠分为5组，使用灌胃法每日按照100mg／kg体重的剂量灌胃TNZ药液，连续5d。

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RESULTS: The effective rate of TNZ delivery device in adult periodontitis patients was 93.33%, which was significantly higher than that of the control group ( 73.33%).

结果：替硝唑棒治疗成人牙周炎的疗效显效率为93.33%，优于对照组73.33%。

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Conclusion TNZ can apparently control periodontitis symptoms and reduce the number of spirochete in oral bacteria.

结论局部应用替硝唑能明显抑制牙周炎症，降低螺旋体在口腔菌群中的比例，口腔螺旋体对替硝唑的敏感度有待进一步实验。

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Comparatively the product TNZ is in inferior position both in production capacity, manufacturing cost as well as in market expanding, product market is shrinking continuously.

替硝唑产品在生产能力、生产成本、市场拓展能力等方面处于相对劣势，产品市场不断痿缩。

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OBJECTIVE To prepare the tinidazole β-cyclodextrin inclusion compound, to improve the stability and solubility of tinidazole ( TNZ).

目的研究替硝唑-β-环糊精包合物的制备工艺。

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Objective To test the effect of TNZ on oral spirochete among 24 patients with severe periodontitis.

目的检测24例重度牙周炎患者口腔螺旋体对替硝唑的敏感性。

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TNZ in plasma and muscle tissues extracted with dichloromethane.

用二氯甲烷萃取血浆和肌肉中TNZ。

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