tgf

BM-MSCs can be induced to chondrogenic differentiation by TGF-of β 3, insulin, sodium pyruvate, vitamin C and dexamethasone in vitro. 3.

骨髓间充质干细胞在体外经TGF-β3、胰岛素、丙酮酸钠、维生素C、地塞米松诱导后可向软骨方向诱导分化。

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The expression of TGF-β 1 and bFGF in the synovial and cartilage was increased and the degree of cartilage destruction was decreased after taking the aqueous components of Chuandilong;

穿地龙的水溶性成分还能增加滑膜及软骨中TGF一p，、bFGF的表达，减缓软骨损伤；

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Conclusion Tranilast could inhibit TGF-β_2 expression in cultured human trabecular meshwork cells.

结论曲尼司特能明显抑制小梁细胞TGFβ2的表达。

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Results TGF � � 1 expression was found in both cytoplasm and extracellular stroma.

结果:tgfβ在宫颈鳞癌细胞浆及细胞外基质中均可见表达.

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C-ski is transcriptional co-repressors that inhibit transforming growth factor-beta ( TGF-beta ) signaling through interaction with Smad 3, Smad 2 protein.

同时,近些年研究表明TGF -beta 信号系统是导致瘢痕形成的重要原因,而Smad3和Smad2做为TGF -beta 途径重要的信号因子,在瘢痕形成中具有重要作用, 因此,抑制Smad3和Smad2成为了减轻瘢痕形成的新途径.

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TGF-P 1 is a polypeptide with many biologic functions, which promotes the synthesis of extracellular matrix ( ECM) and angiogenesis, and inhibits ECM catabolism.

TGFβ1是一种有多种功能的蛋白多肽，它既能刺激细胞外基质的合成，又能抑制新合成的细胞外基质的降解，还能增加血管的形成。

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In all cell lines TGF a induced total EGFR protein levels higher than EGF (? P? < 0.05 ).

各细胞系EGFR蛋白水平TGFα组明显高于EGF组 ( P<0.05 ).

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Conclusion TGF � � 1 may involve in regulation of ocular growth.

结论视网膜tgf- β1的变化可能与FDM的 形成有关,tgf- β1可能参与眼球生长调控.

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The Correlation of TGF-α and NF-κ B with Cardiovascular Remodeling in Elderly Cardiopathy Patients

转化生长因子-α、核因子-κB与老年心血管疾病心血管重构相关性研究

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TGF-� � 1 in Ctrl group did not return to the reference value until 8 weeks after trauma.

对照组TGF - β1水平直至骨折后8周时,才回落至正常水平.

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ConclusionThere is an additive effect but no synergism between IGF-I and TGF-� � 1 on EMT.

IGF-I 和TGF - β1对诱导HKC转化无协同作用.

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Express of TGF-β_1 and ECM in STZ Diabetes Rats

糖尿病大鼠肾组织TGF-β1及细胞外基质表达

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Expression of TGF � � 1 was evaluated by RT PCR technique.

逆转录聚合酶链反应(RT?PCR)方法测定肺组织内TGF?β1的表达.

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Survival rate for positive staining group of TGF | � � RI was better than negative group ( P & lt ; 0.01 ).

TGFβ R 阳性者术后3、5年生存率优于阴性者.

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The mRNA expression of TGF-b 1 was determined by semi-quantification reverse transcriptive PCR ( RT-PCR ).

采用逆转录多聚酶链式反应 ( RT-PCR ) 半定量分析HPMC中TGF-1mRNA的表达.

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Conclusions: CPL can inhibit the transcription of TGF-� � _ 1.

结论: CPL可 明显下调实验性肝纤维化大鼠肝组织TGF - β_1mRNA的表达.

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Conclusion: TGF-� � directly induces the expression of CTGF and ECM components in HMCs.

结论: HMCs可表达CTGF. TGF - β可诱导体外培养的HMCsCTGF及 ECM成分高表达.

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Expression of TGF � � 1 mRNA was evaluated by RT PCR.

RT?PCR方法测定肺组织内TGF?β1的表达.

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Simvastatin may effectively attenuate DN progression through down-regulating the expression of TGF-� � via p 38 MAPK.

斯伐他汀可能通过抑制p38MAPK磷酸化而减少TGF - β的蛋白表达.

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Transforming growth factor β( TGF-β) initiates its diverse cellular responses by binding to and activating specific cell surface receptors that have intrinsic serine/ threonine kinase activity.

转化生长因子β（transforming growth factor-，βTGF-β）可通过特异性结合并激活具有丝氨酸/苏氨酸激酶活性的细胞表面受体启动各种应答。

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Relationship between TGF β 1, serum indexes of liver fibrosis and hepatic tissue pathology in patients with chronic liver diseases

慢性肝病患者血清TGF-β1与肝纤维化指标和肝组织病理的关系

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Methods: Using cell culture and Western blot, the TGF-� � 1-induced expression of FN and ILK was tested.

方法培养人肾小管上皮细胞(HKC),用蛋白印迹方法检测TGF - β1诱导HKC合成 FN和表达ILK的作用.

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Pilot Research of Diagnostic Effect of TGF-β_1 Detection in ANA Positive Autoimmune Diseases

TGF-β1在ANA阳性自身免疫病中的诊断意义初探

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The expression of TGF � � _ 1 in BEC increased in both COPD ( 0.785±0.071 ) and chronic bronchitis ( 0.559±0.051 ) groups compared to control ( 0.195±0.029 ) ( P < 0.05 ).

COPD 组、慢支组气道上皮细胞TGF-β1的表达明显高于对照组 ( 0.195±0.029 ),差异有显著性P<0.05.

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With the coordinate effect of TGF-β 1 and gelatinase, the formation of posterior capsule opacification can be speed up.

TGFβ1和明胶酶共同作用，可能加速后发性白内障的形成。

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The effect of Benazepril alone or combining with Irbesartan on TGF β 3 mRNA expression in myocardium and renal cortex of rats

苯那普利单用及与伊贝沙坦合用对SHR心肌、肾皮质TGFβ3mRNA表达的影响

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Conclusion E2 can inhibit obviously the formation of liver fibrosis induced by CCl_4 in rats, which may be relateed to inhibiting the activation of hepatic stellate cells and decreasing the proteinic expressions of TGF β_1, uPA and PAI-1.

结论地龙2号可能通过抑制肝纤维化大鼠肝组织中肝星状细胞的活化，降低TGFβ1、uPA及PAI1的表达，发挥抗肝纤维化作用。

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Objective To study the possible role of bone morphogenetic protein 7 ( BMP 7) in the TGF β 1 induced tubular epithelial myofibroblast transdifferentiation ( TEMT) of cultured renal tubular epithelial cells.

目的观察骨成形蛋白7（BMP-7）对TGF-β1诱导的人肾小管上皮细胞转分化的影响，以探讨其延缓小管间质纤维化病变的作用及其可能机制。

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Effects of FK506 on transdifferentiation and NF-κ B activity of human tubular cells induced by TGF-β in vitro

他克莫司对转化生长因子-β诱导的肾小管上皮细胞转分化的抑制作用及对核因子-κB活性的影响

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The results also suggest that MCP-1 induced EMT may involve the TGF-� � 1-independant pathway of the cells.

同时提示MCP1诱导的转分化可能涉及非TGFβ依赖的细胞信号传导途径,需进一步研究.

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