telomeric

Detection of telomerase activity in breast carcinoma by silver-staining telomeric repeat amplification protocol

银染端粒重复扩增技术检测乳腺癌组织端粒酶活性的研究

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The molecular interaction between P53 and telomeric repeat binding protein 1 in vitro

P53与端粒重复序列结合蛋白质1的体外相互作用

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Construction and expression of telomeric repeat binding factor 2 small interfering RNA eukaryotic vector

TRF2小干扰RNA载体的构建及表达

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Expression of fibronectin gene in pancreas carcinoma Human Telomeric Protein

人粘连蛋白基因在胰腺癌中的表达

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A quantitative method to measure telomerase activity by bioluminescence connected with telomeric repeat amplification protocol

端粒重复扩增生物发光分析法定量检测端粒酶活性

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Methods Telomerase activity in 28 specimens of cervical carcinoma, 6 specimens of cervical dysplasia and 10 specimens of normal cervical tissues were detected by PCR based sliver staining Telomeric repeat Amplification Protocal ( TRAP).

方法：采用PCR TRAP方法对28例宫颈癌组织，10例正常宫颈组织，6例宫颈不典型增生组织的端粒酶活性进行检测。

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Minute Chromosome Rearrangement Detected by Human Telomeric Band Painting Probes

应用端粒区带涂染探针检测染色体微小结构重排

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Telomeric loss in head and neck squamous cell carcinomas

染色体端粒的缺失表达在头颈部磷癌的意义

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The reverse transcriptase telomerase is able to maintain stable telomeric length and essential for the unlimited proliferation of tumor cells. Telomerase activity has been detected in 85-90% of human tumors and tumor-derived cell lines but not in most human somatic cells.

端粒酶表达于85%以上的肿瘤细胞中，能够维持细胞中端粒的长度，对永生化细胞的增殖具有重要作用，而在大多数人正常体细胞中却没有表达。

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Analysis of telomeric restriction fragment in gastric cancer and its premalignant lesions

胃癌及癌前组织端粒状态的分析

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Specific Attachment of Telomeric DNA to Nuclear Matrix in Hela Cells

HeLa细胞染色体端粒DNA与核骨架的特异性结合

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Advances in the regulation mechanism of the telomeric length

端粒长度调控机制的研究进展

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We report the identification of a splice donor mutation in a novel gene, which is the mouse ortholog of a newly discovered telomeric regulator.

我们报告了一个新基因左拼接剪接变异的证据，这个新基因是一个新发现的鼠同源基因端粒调节体。

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Therefore, normal human cells lack telomerase activity, their telomeric DNA lengths decrease gradually with the increasing numbers of cell divisions, eventually telomeres shortening induce cellular replicative senescence.

因此正常人体细胞缺乏端粒酶活性，端粒DNA长度随细胞分裂次数增多逐渐缩短，最终引起细胞复制衰老。

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Preparation and characterization of monoclonal antibody against human telomeric repeat binding factor 1

抗人端粒重复序列结合因子（TRF1~（33-277））单克隆抗体的制备及生物学特性初步鉴定

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Objective: Telomerase is a ribonucleoprotein complex that synthesizes telomeric DNA onto chromosome ends using its RNA component as template, enabling extension of cell lifespan and even immortalization.

目的：端粒酶是一种核糖核蛋白复合物，能以自身RNA成分为模板催化染色体末端端粒重复序列的延伸，使细胞得以持续增殖甚至永生化。

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Primary Study on Spectrophotometric Detection of Telomeric DNA with Catalytic Beacons

催化信标检测端粒DNA序列的初步研究

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Construction of antisense human telomeric RNA retroviral vector and its inhibition on colorectal cancer cells

反义人类端粒酶RNA逆转录病毒载体构建及其对结直肠癌细胞的抑制作用

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Study on the mutation of human telomeric repeat binding factor 1 gene in malignant hematopoietic cell lines

恶性血液病细胞株人端粒重复序列结合因子基因突变情况的研究

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Expression of telomerase reverse transcriptase and telomeric repeat binding factor 2 during rat myocardial development

端粒酶逆转录酶和端粒重复结合因子2在大鼠心肌细胞发育过程中的表达

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Detection of telomerase activity in human lung cancer by silver staining telomeric repeat amplification protocol

银染端粒重复序列扩增法检测肺癌端粒酶活性

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Methods: Thirty-four non-Hodgkin's lymphoma and 6 Hodgkin's diseases were examined for telomerase activity by means of telomeric repeat amplification protocol ( TRAP) assay based on PCR.

方法采用PCR TRAP方法检验34例非霍奇金淋巴瘤和6例霍奇金病的端粒酶活性。

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A PCR based telomeric repeat amplification protocol ( TRAP) was used for assaying telomerase activity.

用端粒重复扩增（TRAP）PCR法测定细胞的端粒酶活性。

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Comparison and observation on chromosome telomeric associations in human lung cancer

人肺癌染色体端粒联合的比较观察

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Improvement& Application of Telomeric Repeat Amplification Protocol ( TRAP) and Research on Telomerase characteristic

端粒重复扩增程序（TRAP）的改进和应用以及端粒酶酶学性质研究

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In vitro binding of p53 and telomeric repeat factor 2

端粒重复因子2与p53的体外结合

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The role of telomeric length alteration in salivary tumor transformation

端粒长度变化在涎腺肿瘤发生中的作用

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Measurement of the Telomeric Length of Hemangioma and Embryonic Kidney Endothelium

血管瘤和人胚肾血管内皮细胞端粒长度测定

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Study on the genome structure of human telomeric repeat binding factor 1 and its pseudogenes

人端粒重复序列结合因子基因组和假基因研究

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Methods: The telomeric repeat amplification protocol ( TRAP ) combined with densitometry and clinical examination were performed in leukemia patients.

方法: 端粒重复扩增法结合吸光度测定及临床病例分析.

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