postsynaptic

Mining the postsynaptic proteome now gives researchers a strategic entry point, and the rest of us a front row seat to witness neuroscience unravel the complexity of human brain disorders.

对突触后蛋白质组学的研究，给了目前的研究者们一个策略上的新切入点，并让我们得以见证当代神经科学对人类脑部疾病的复杂成因层层解密的过程。

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OBJECTIVE To observe the effect of electrical acupuncture on long-term potentiation ( LTP) of excitatory postsynaptic potential ( EPSP) of normal rats and rats with hypomnesia induced by scopolamine.

目的观察电针对麻醉状态下正常和东莨菪碱引起的学习记忆减退模型大鼠海马突触EPSP长时程增强（LTP）的作用。

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Synapses are connections between neurons, biological signals are transferred from the presynaptic membrane by the synaptic transmission to the postsynaptic membrane.

突触是神经元之间的连接部位，生物信号从突触前膜经突触传递到突触后膜。

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The excitatory postsynaptic potential ( EPSP) input-output relationship curve ( I-O curve) slope was significantly increased in the FPI-ipsilateral group, compared with the other two groups ( P < 0.05).

FPI损伤同侧组兴奋性输入-输出关系曲线的斜率比其他两组显著增大（P<0.05）；

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Effects of binocular form deprivation on neuron excitory postsynaptic currents in adult visual cortex

双眼形觉剥夺对成年大鼠视皮层兴奋性突触后电流的影响

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PubMed abstract: Long-term potentiation ( LTP) is an enhancement of synaptic strength that can be produced by pairing of presynaptic activity with postsynaptic depolarization.

《公共医学图书馆摘要》：长期电位化（LTP）以前突触活动联对后突触除极化，增加突触讯号强度。

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The results showed that the differences of potentiation of excited postsynaptic potentials ( EPSPs) were not significant among the five groups ( P> 0.05), and potentiation of population spike ( PS) amplitude in BYD groups were significantly different from AD model group.

结果表明：强直刺激后，各组间兴奋性突触后电位增强差异不明显（P>0.05），补肾益智方高、低剂量组群体峰电位幅度增强较模型组明显提高（P

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A significant reduction in the number of synaptic with nuclear presynaptic membrane and postsynaptic membrane, and a low density in postsynaptic dense zone.

模型组神经元突触数量明显减少，突触前、后膜结构模糊不清，突触后致密区密度低。

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Neurotransmitter receptors mediate signal transduction postsynaptic membrane of synaptic connections between neurons in the nervous system.

大脑中神经元突触间的信号传递是由许多神经递质受体介导的.

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Effects of TFG on the Late Slow Excitatory Postsynaptic Potential of the Neurons in Inferior Mesenteric Ganglion of Guinea-pig in Vitro; The Research of Bile Metabolism after Cholecystectomy

银杏叶总黄酮对豚鼠肠系膜下神经节细胞ls-EPSP的影响胆囊切除术后豚鼠肠道推进功能及胆汁代谢变化的实验研究

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After application AP-5 or KYN to block depolarization in the postsynaptic cells, conditioning stimulation still induced LTP.

应用AP-5或KYN阻断突触后神经元的去极化后仍然可在MGB成功诱导出LTP；

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Postsynaptic potentials manifested current effect and frequency dependency and their IPSP displayed a prolonged inhibition.

突触后电位表现电流效应和频率依赖性，其IPSP具有长时程的抑制作用。

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The IEI analysis by time-IEI graphs and return maps showed that the main temporal structure of presynaptic input trains could be detected in postsynaptic output trains, especially under brief-burst stimulation.

用时间-IEI图与回归映射的方法分析IEI序列，结果表明在突触后输出脉冲序列中可以检测到突触前脉冲序列的主要时间结构特征，特别是在短簇脉冲作为刺激单位时。

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Effect of Electrical Acupuncture on Long-term Potentiation of Excitatory Postsynaptic Potential of Rat Hippocampus

电针对大鼠海马兴奋性突触后电位长时程增强的作用

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Maturation of presynaptic transmitter secretion machinery and trafficking of postsynaptic receptors are two critical steps in synaptogenesis and synaptic development of central nervous system ( CNS).

突触前递质释放装置的发育成熟和突触后受体的转运是中枢神经系统突触发育过程中非常重要的两个方面。

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In the past, study of postsynaptic regulatory mechanism is rare.

以往的研究多侧重于突触前和突触间隙调节机制，而对突触后调节机制研究不多。

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Influence of Stimulating of Nerve of Hind Limb on Intracellular Potentials of the Neurons in Primary Sensory Cortex ( S ⅰ) of Cat: Excitatory Postsynaptic Potentials and Spikes

刺激猫后肢神经对皮层体感一区伤害感受神经元细胞内电位的影响&兴奋性突触后电位及锋电位

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The primary function of the presynaptic nerve terminals is to release quantum transmitter and thus activate the postsynaptic target cell.

突触前神经末梢的主要作用是以量子方式释放神经递质，并以此激活突触后的靶细胞。

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Presynaptic [ Ca 2+] I could influence the replacing of presynaptic depressed vesicles, as well as encode the precise relative timing of presynaptic input and postsynaptic activity and generate long term synaptic modification of opposite polarity ( LTP or LTD).

突触前[Ca2+]i可以影响被抑制的突触前膜囊泡的更新，并准确编码突触前和突触后信息，产生截然相反的长时程突触修饰（LTP或LTD）。

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Endogenous hydrogen sulfide ( H2S) can increase the production of cAMP, potentiate the exciting postsynaptic potential mediated by NMDA receptor and enhance the induction of hippocampal long-term potentiation.

内源性硫化氢（H2S）可以刺激神经细胞cAMP水平增加，提高NMDA受体介导的突触后兴奋性电位，提高诱导海马长时程增强。

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However, the drug assay deduced the postsynaptic receptors are hypersensitive, which indicates some other kinds of receptors other than the ionotropic receptors are affected in sec-10 mutant.

但是药学实验的结果却能够推论出sec-10基因突变种系的突触后膜上受体过度敏感，我们推测是由于突触后膜上离子型受体以外的其他类型受体受到了影响。

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In this case, the CA-bouton was presynaptic element whereas the VP-bouton served as postsynaptic element.

在这种情况下，含CA的神经终末为突触前成分，含VP的神经终末为突触后成分。

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Results The length of postsynaptic membrane decreased obviously. The ratio of the length of postsynaptic with presynaptic membrane, and that the motor nerve terminal area with postsynaptic membrane area diminished. The AChR on the postsynaptic membrane decreased by 35.9 percent as well.

结果MG时突触后膜长度缩短，后、前膜长度比值变小，神经末端面积及其与突触后膜面积之比变小，突触后膜上的乙酰胆碱受体（AChR）减少了35.9%。

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And the opening proportion of chemical-gated ion channels on postsynaptic membrane was positively related to the potential of presynaptic membrane.

突触后膜上化学门控离子通道的开放比例与突触前膜电位呈正相关；

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Methods After stimulating auditory thalamic radiation, excitatory postsynaptic currents ( EPSCs) were recorded at MGB neurons using whole-cell patch clamp technique in AC-MGB slices.

方法刺激听辐射纤维，采用脑片膜片钳全细胞技术在MGB分离和记录兴奋性突触后电流（EPSCs）；

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Correlated pre-and postsynaptic activity that induces long-term potentiation is known to induce a persistent enhancement of the intrinsic excitability of the presynaptic neuron.

突触前-后神经元的相关活动能够诱导长时程增强（LTP）现象，同时也可以持续的提高突触前神经元内在兴奋性。

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Population spike ( PS) amplitude and field excitatory postsynaptic potential ( fEPSP) slope were used to indicate the LTP changes.

以群体峰电位（PS）的幅值和场兴奋性突触后电位（fEPSP）的斜率作为观察LTP变化的指标。

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The postsynaptic membrane of S-, T-and G-types is apparently thicker than the presynaptic membrane and showed to be asymmetrical.

S型、T型和G型突触后膜均比前膜明显增厚，呈不对称性。

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Conclusion: The larger curved contact surfaces of perforated synapses and projectin to pre synaptic area, as well as the thicker postsynaptic densities with subsynaptic dense bodies were consider as the morphological feature of synaptogenesis and its plasticity.

结论：穿孔突触接触面曲度较大，并凸向突触前区域，突触后致密物质较厚，可见突触下致密小体，均可作突触发育和可塑性突触的形态特征。

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Objective To study the electrophysiological properties of postsynaptic neurons from layer ⅱ-ⅲ in normal rat visual cortex during the critical period of visual plasticity and its relationship with age and visual experiences and to explore the synaptic and cellular mechanisms of experience-dependent plasticity in visual cortex.

目的研究大鼠视觉发育可塑性关键期视皮层Ⅱ-Ⅲ层神经元的电学特性变化及其与大鼠生理年龄及视觉经验的关系，探索视皮层经验依赖性可塑性的突触和细胞机制。

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