1、

Enhancing Effect of Chinese Herbal Medicine Active Components on Suicide Gene Bystander Effect and the Mechanism Study

中药活性成分对自杀基因旁观者效应增效作用及机制研究

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2、

Killing Effect of Human Pulmonary Adenocarcinoma Cells with TK+ CD/ 5-Fc+ GCV Coexpression Suicide Gene Systems

自杀基因CD、TK的共表达对人肺腺癌细胞的杀伤作用

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3、

CD/ 5-FC suicide gene therapy system mediated by Bifidobacterium Infantis was noted to have good antitumor effect on melanoma.

婴儿双歧杆菌介导的CD/5-FC自杀基因系统对黑色素瘤具有明显的抑瘤效果。

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4、

Effects of CD/ 5-FC suicide gene therapy system on human malignant glioma cells in vitro

CD/5-FC自杀基因治疗系统体外杀伤恶性人脑胶质瘤细胞作用的研究

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5、

Gene therapy in vivo for hepatocellular carcinoma using double suicide genes combined with IL-12 gene

HSV-TK/CD基因联合IL-12基因体内治疗肝癌

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6、

Followed the prodrug fludarabine incubation, the cytotoxic effect, bystander effect and apoptosis induction of PNP/ fludarabine suicide gene system on BEL7402 cells were detected by methyl thiazolyl tetrazolium ( MTT) colorimetric method and Annexin V-FITC apoptosis detection kit, respectively.

分别应用四甲基偶氮唑蓝(MTT)比色法和Annexin V鄄FITC凋亡检测试剂盒检测PNP/fludarabine自杀基因系统对BEL7402细胞的细胞毒效应、旁观者效应和诱导凋亡作用。

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7、

Suicide gene therapy for glioma using HSV tk/ GCV system

HSV-tk/GCV系统对神经胶质瘤的自杀基因治疗研究

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8、

The development of herpes simplex virus thymidine kinase suicide gene imaging

单纯疱疹病毒胸苷激酶自杀基因显像研究进展

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9、

Experimental studies of using adenovirus-mediated cd/ 5-fc suicide gene in treatment of pan-creatic cancer

CD/5-FC自杀基因系统治疗胰腺癌的实验研究

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10、

At present, the most mature research of suicide gene systems are HSV-TK/ GCV and CD/ 5-FC.

目前研究最为成熟的自杀基因系统是HSV-TK/GCV和CD/5-FC。

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11、

Killing effect of combined application of double suicide gene/ prodrug systems and radiotherapy on osteosarcoma cells

联合应用自杀基因/前药系统和放疗对人骨肉瘤细胞的杀伤作用

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12、

Combining FCU/ 5-FU suicide gene/ prodrug system and radiation in treating nasopharyngeal carcinoma: an experimental study

FCU/5-氟胞嘧啶自杀基因前体药物系统联合放射治疗鼻咽癌的实验研究

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13、

Research and progress on suicide gene therapy for pancreatic tumor

自杀基因在胰腺癌治疗中的研究进展

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14、

Suicide gene therapy, also known as gene-directed enzyme prodrug therapy, is an important strategy for tumor treatment by improving the specifical concentrations of drugs in tumors and a unique bystander effect.

自杀基因疗法,又名基因介导的酶-前药疗法,能特异性提高药物在肿瘤中的浓度,并具备独特的旁观者效应,是肿瘤基因治疗的重要方法之一。

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15、

Therefore enhancing the bystander effect has become an important strategy to raise curative effect of the suicide gene therapy.

因此,增强旁观者效应已成为提高肿瘤自杀基因治疗疗效的重要策略。

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16、

Relationship between the expression of connexin 43 and bystander effect of suicide gene therapy in ovarian cancer

卵巢癌自杀基因治疗的旁观者效应及其与间隙连接蛋白43表达的关系

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17、

Construction of HSV-tk/ GCV suicide gene system for hepatocarcinoma cells and its bystander effect in rats

大鼠肝癌细胞HSV-tk/GCV自杀基因系统的构建及其旁观者效应

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18、

The Enhancing Utility and Mechanism Research of Curcumin on Bystander Effect of HSV-tk/ GCV Suicide Gene System

姜黄素对tk/GCV自杀基因系统旁观者效应的增效作用及机制

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19、

Conclusion Recombinant Bifidobacterium Infantis with UPRT gene can significantly enhance the killing effect of CD/ 5-FC suicide gene system on melanoma B16-F10 cells of mice.

结论婴儿双歧杆菌联合转导UPRT基因可明显增强CD/5-FC自杀基因系统对鼠黑色素瘤细胞B16-F10的杀伤作用。

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20、

Bystander effect in suicide gene therapy for glioma

恶性胶质瘤自杀基因治疗中旁效应的机理

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