HHD

[ HT5H] Conclusion [ HT5SS] The study indicated that HHD can decrease the apoptosis of chondrocytes in the late stage of OA and keep the balance of proliferation and apoptosis of OA chondrocytes.

结论长期服用黑虎丹能减少晚期OA软骨细胞的凋亡，并维持OA软骨细胞增殖和凋亡的平衡。

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GFAP + astrocytes hhd no changes and there were no VIM + astrocytes surrounding wounds in postmortem groups.

死后脑干损伤组GFAP+星形胶质细胞无改变,创缘及创周无VIM+星形胶质细胞出现.

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Background Familial benign chronic pemphigus or Hailey-Hailey disease ( HHD; OMIM 169600) is a rare autosomal dominant cutaneous disorder characterized by recurrent vesicles and erosions mainly in intertriginous areas.

研究背景：家族性慢性良性天疱疮，又称Hailey-Hailey病（HHD，OMIM169600）是一种罕见的常染色体显性遗传性皮肤病。

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【 Results 】 HSP_ ( 70) expression in HHD group and heat shock group was higher than that in the model group ( P < 0.05 or P < 0.01).

【结果】白花蛇舌草组及热休克处理组H22肝癌细胞HSP70的表达显著性高于模型组（P<0.05或P<0.01）；

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GFAP + astrocytes hhd no changes and there were no VIM + astrocytes in postmortem groups.

死后脑干损伤组GFAP+星形胶质细胞无改变,创缘及创周无vim+星形胶质细胞出现.

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Conclusion Most of HHD lead to cardiac enlargement. Left atrial enlargement can be found mostly, and right ventricular enlargement is more often than left ventricular enlargement.

结论HHD可引起不同房室腔扩大，左房扩大最常见，右室扩大多于左室扩大；

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Finally, the etiology, clinical features, diagnosis and treatmentof HHD were discussed.

最后, 讨论了HHD的病因 、 临床特点 、 诊断及治疗.

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Impairment of LV function and synchrony existed only in diastole in HHD patients.

HHD仅于舒张期出现左室心肌功能下降及运动的不协调性.

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Biological therapy , such as anti IL-6 antibody, has a good prospect in the treatment of HHD.

抗白介素 -6 抗体等生物学疗效有望治疗本病.

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