EIOP

The expressions of the MHO II antigen in the glia of the retina of each group differ greatly, with negative expression in control rats and positive expression in certain layers of placebo-immunized chronic EIOP rats and COP-1-immunized chronic EIOP rats.

慢性高眼压组动物眼球的切片上染色阳性的RGCS数量少于安慰剂免疫的慢性高眼压组（P<0.05）。4、3组模型大鼠视网膜小胶质细胞表达MHC一11抗原表达有明显差异。

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To establish reliable copolymer-1 ( COP-1 )-immunized chronic EIOP rats models.

建立 COP -1 免疫的慢性高眼压大鼠模型.

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To detect the normal intraocular pressure ( IOP) and establish reliable chronic elevated intraocular pressure ( EIOP) rat models.

观测大鼠正常眼压值，建立稳定的大鼠慢性高眼压模型。

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CONCLUSION: The autoimmune response induced by COP 1 protects the RGCs from apoptosis under the condition of chronic EIOP and results in increased IL 6R expression on RGCs.

结论：COP1诱导的自身免疫对慢性EIOP条件下的RGC具有保护作用，并可使RGC表达IL6R的水平升高。

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To establish reliable copolymer-1 ( COP-1)-immunized chronic EIOP rats models. 3.

建立COP-1免疫的慢性高眼压大鼠模型。

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To inspect the expression of the MHC-II antigen in the glia of the retina of chronic EIOP rat models: control rats, placebo-immunized chronic EIOP rats and COP-1-immunized chronic EIOP rats. 5.

检测正常大鼠、安慰剂免疫的慢性高眼压大鼠和COP-1免疫的慢性高眼压大鼠视网膜神经胶质细胞表达MHC-Ⅱ抗原的变化。

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Cauterization of episcleral vein was used to set up rat's EIOP model.

应用烧灼巩膜静脉的方法制作大鼠慢性EIOP模型。

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