wnt

The tempo and spatial expression profiles of MuSKand Dvl are similar in muscle.

Dvl是Wnt信号传递途径中的重要分子.它在发育过程中的表达分布和MuSK相似,富集于神经肌肉接头.

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Mechanism of the WNT Family in Vertebrate Skeleton Development

WNT家族在脊椎动物骨骼发育中的作用机制

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One is as a structural component of adherens junction, which forms the cadherin-catenin complex to mediate intercellular adhesion. The other is as a downstream effector of Wnt signaling pathway, which controls essential steps in many aspects of embryogenesis and tumorigenesis.

一是作为附着连接的组成部分，与钙粘蛋白结合形成复合体参与细胞间连接；二是作为信号分子，是Wnt信号途径的重要环节，在胚胎发育和肿瘤发生中起重要作用。

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The decision of the cell fate specification in the developing vertebrate inner ear is dependent on complex regulatory genetic pathways involving in the Wnt families.

在脊椎动物的内耳发育中，细胞分化命运的决定有赖于复杂的基因调节通路，此调节通路涉及Wnt家族。

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Noncanonical Wnt signaling was highly expressed in the radiation induced cellular senescence of mesenchymal stem cells, which indicate that noncanonical Wnt signaling may be involved in the radiation induced cellular senescence.

间充质干细胞放射后衰老细胞中非经典Wnt信号高表达，非经典Wnt信号可能参与了间充质干细胞放射后衰老的过程。

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Thisstudy used RNA interference ( RNAi ) to detect the function of Wnt 5 band Fzd 4 during the adipogenesis differentiation processes.

最近研究又表明Wnt家族 分子与脂肪代谢有密切关系,本试验应用 RNAi 的方法研究Wnt家族 中的Wnt5b和受体Fzd4在脂肪代谢中的作用.

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With the perfection of wireless network technology ( WNT), the traditional E business pattern is facing the transformation from the wire form to the mobile form.

随着无线网络技术的完善，如今传统的电子商务模式面临着一次新的革命，即从有线的电子商务形式到移动的电子商务形式，人们的生活状态又将发生巨大的改变。

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SiRNA Inhibition Wnt-1 Gene and Its Effect in Human Lung Adenocarcinoma Cell Line A2

siRNA抑制Wnt-1基因对人肺腺癌细胞株A2的影响

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However, both the members of WNT family and their related molecules in the signaling pathway expressing abnormally can disrupt the balance remained by the WNT family and result in skeleton malformation.

在WNT家族及其作用途径的相关信号分子中，无论何种亚型或分子的异常表达都可能破坏WNT系统维系的正负平衡机制，导致骨骼系统畸形。

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Objective: To explore the role of Frizzled receptor of Wnt in the development of spinal cord in mouse.

目的：探讨Wnt信号分子受体Frizzled在小鼠脊髓发育中的作用。

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Today we tell about the expression down to earth.

今天我们讲短语“downtoearth”(坦诚低调).

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This experiment proved that, Wnt signaling pathway plays an important role in mouse molar development, especially the development of ameloblast.

本实验证明了Wnt信号通路在小鼠磨牙发育，特别是在成釉质细胞的发育过程中起着重要的作用。

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To study the effect and mechanism of Wnt/ β-catenin signaling pathway in proliferation and differentiation of EC, could explain the molecular mechanism of the formation of teratocarcinoma, provide effective experimental evidence to genetic diagnosis and therapy in teratocarcinoma and germ cell tumors.

探讨Wnt/β-catenin在EC增殖和分化中的作用和作用机制，不仅有助于阐明畸胎癌形成的分子调控机制，而且能为畸胎癌及相关生殖细胞肿瘤的基因靶向治疗提供有效的实验依据。

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Its molecular mechanism may be that through the reduction of nuclear β-catenin, curcumin can block the Wnt signal transduction pathway and inhibit the expression of c-myc gene, a downstream target gene, to prevent lung cancer cells to enter S phase from G1 phase.

其分子学机制可能是姜黄素通过减少核蛋白β-catenin，阻断Wnt信号转导通路，抑制下游靶基因c-myc的表达，进而阻止肺癌细胞由G1期进入S期。

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It is known that other members of LEF/ TCF family all have different isoforms, and in their C termini may generate an extremely important alternative domain necessary for the repression and/ or activation of a select subset of Wnt target genes.

研究表明TCF家族其他成员均具有多种不同形式异构体，并且其羧基端可形成选择性功能域，对抑制或活化选择性的Wnt靶基因起着必需的作用。

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We observed a widespread oscillatory-like pattern of changes in gene expression, involving components of both the canonical and the noncanonical Wnt signaling pathways.

我们看到一个广泛的oscillatory-like模式的变化，包括组件进行基因表达两种典型和经典之中Wnt信号传导通路。

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Another expression linked to sailing is batten down the hatches.

另一个和航海相关的词语是battendownthehatches(做好准备).

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Experimental Study of the Relationship between WNT Signaling Pathway and Basal Cell Carcinoma

WNT信号传导通路与基底细胞癌关系的研究

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Wnt signalling is involved throughout development and may be inappropriately activated in a variety of human cancers.

Wnt信号涉及参与整个发育过程，在各种癌症中它会被不适当地激活。

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