signaling pathway

This experiment proved that, Wnt signaling pathway plays an important role in mouse molar development, especially the development of ameloblast.

本实验证明了Wnt信号通路在小鼠磨牙发育，特别是在成釉质细胞的发育过程中起着重要的作用。

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CREG Modulates Apoptosis of Human Vascular Smooth Muscle Cells via p38/ JNK MAPK Signaling Pathway

CREG通过p38/JNK丝裂原活化蛋白激酶信号通路调控血管平滑肌细胞凋亡

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Conclusions LXR signaling pathway may play important role in the maintenance of cerebral balance.

结论LXR信号传导途径在维护脑内环境平衡方面起重要作用。

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Activation of cytokines in the OPG/ RANK/ RANKL signaling pathway, including OPG and RANKL, etc., indirectly inhibit the apoptosis of osteoclasts and promote bone resorption, Subsequently, the spinal vertebrae linear growth was reduced.

通过激活OPG/RANK/RANKL信号通路中多种细胞因子，主要包括OPG和RANKL等，间接抑制破骨细胞的凋亡，进而促进骨吸收，抑制脊柱椎体的线性生长。

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Objective To investigate the role of p38 MAPK signaling pathway in interleukin ( IL)-1 β induced transdifferentiation and its functional influences in human renal proximal tubular cell line HK-2 cells.

目的探讨p38MAPK信号转导途径对IL1β诱导肾小管上皮细胞转分化的影响及其导致的功能改变。

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Study of Regulation of DAG/ PKC Signaling Pathway

DAG/PKC信号转导途径调控机制的初步研究

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Under low-fat diet, adiponectin signaling pathway components exhibited circadian rhythmicity.

在低脂肪饮食, 脂联素信号转导通路组成部分展出昼夜节律性.

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PI3K/ Akt signaling pathway was activated in Pten-deficient articular chondrocytes. The Pten knockout mice gradually exhibit humpback, faltering steps and anchylosis as they grew up.

Pten敲除小鼠的关节软骨细胞中PI3K/Akt信号通路持续激活，成年的Pten敲除小鼠逐步表现出驼背、步履蹒跚、关节僵硬等OA大体表现。

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Objective: To study the influence of dietary restriction on the expression of insulin signaling pathway genes in mouse adipose tissue.

目的：研究限食对脂肪组织胰岛素信号通路基因表达的影响。

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It is known that DAG/ PKC signaling pathway is very important in signal regulating network in cells.

DAG／PKC信号转导通路在细胞内信号调控网络中具有重要作用，是参与细胞生长、增殖、分裂调控的重要信号通路之一，并广泛分布于各种组织细胞。

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PI3k/ AKT signaling pathway may play an important role in it.

PI3k/AKT信号传导通路可能在其抗凋亡中发挥重要的作用。

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Ligands Dependent Activity of Hedgehog Signaling Pathway is Altered in Colorectal Tumors Correlating to Epigenetic Regulation Mechanism

结直肠癌中Hedgehog信号通路的配体依赖性活性改变及其表观修饰机制研究

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UV B signaling pathway and specific UV B receptor, DNA damage, activation of transposons, molecular damage of photosynthetic apparatus and UV B regulation of related gene expression were included.

主要讨论了UV-B信号途径及光受体，UV-B诱导的DNA损伤、转座子激活，UV-B对光合器官的分子伤害及相关基因表达的调控等。

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The findings reveal that Ca2+ signaling may play an important role in Cd in the activation of autophagy and Akt/ mTOR pathway in Cd-induced neuronal cells.

提示：钙离子信号转导在镉诱导神经细胞自噬和mTOR通路激活中有重要作用。

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PIP_2 is a pivotal regulator in cell signaling pathway. DAG and IP_3, which are generated from PIP_2 hydrolysis by PLC, act as second messengers to activate PKC and induce intracellular Ca release, respectively.

PIP2是细胞信号转导通路中的关键调节因子，经磷脂酶C（PLC）水解后可生成DAG及IP3，二者可作为第二信使，分别激活PKC与促使细胞内钙库释钙。

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However, both the members of WNT family and their related molecules in the signaling pathway expressing abnormally can disrupt the balance remained by the WNT family and result in skeleton malformation.

在WNT家族及其作用途径的相关信号分子中，无论何种亚型或分子的异常表达都可能破坏WNT系统维系的正负平衡机制，导致骨骼系统畸形。

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Blocking of Akt signaling pathway can induce apoptosis and growth inhibition of cancer cells.

Akt信号传导途径被抑制之后，可引起肿瘤细胞的凋亡和生长抑制。

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Rac-1/ MMP-2 signaling pathway plays a positive role in tumor cell invasion and metastasis.

Rac1/MMP2通路在卵巢癌的侵袭转移中起着重要作用。

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We wanted to come back and enhance the signaling pathway that makes estrogen functional.

我们想还原大脑的通路，并增强雌激素发挥功能的信号通路。

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Extracellular signal-regulated kinase ( ERK ) signaling pathway is a critical signaling pathway that transduce the intracellular signal.

细胞外信号调节激 酶 信号通道是一条重要的细胞内传导通道.

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Intracellular OAS/ RNaseL signaling pathway plays an important role in host innate immune response by controlling flavivirus, reovirus and encephalomyocarditis virus.

细胞内的OAS/RNaseL信号通路在宿主控制黄病毒、呼肠孤病毒和脑心肌炎病毒的先天性免疫反应中起重要作用。

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Effect of Resistance Training on Akt/ mTOR Signaling Pathway of Aging Mice Cardiac Sarcopenia

抗阻训练对衰老小鼠心肌Sarcopenia中Akt/mTOR信号通路的影响

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Notch Signaling Pathway and Multiple Myeloma& Review

Notch信号通路和多发性骨髓瘤

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To study the effect and mechanism of Wnt/ β-catenin signaling pathway in proliferation and differentiation of EC, could explain the molecular mechanism of the formation of teratocarcinoma, provide effective experimental evidence to genetic diagnosis and therapy in teratocarcinoma and germ cell tumors.

探讨Wnt/β-catenin在EC增殖和分化中的作用和作用机制，不仅有助于阐明畸胎癌形成的分子调控机制，而且能为畸胎癌及相关生殖细胞肿瘤的基因靶向治疗提供有效的实验依据。

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In NO signaling pathway, aconitase was a major NO target or sensor, and the activities of aconitase were also known to be inhibited rapidly by H2O2 and other ROS in animals.

动物顺乌头酸酶是NO信号转导过程中的一个重要靶酶和效应器，并且H2O2能迅速抑制其活性。

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Notch signaling pathway is an evolutionarily highly conserved mechanism for cell-cell communication, which controls differentiation and proliferation, and plays an important role in embryogenesis and many types of cell fate determination.

Notch信号是一个在进化中高度保守的反映细胞间通讯机制的通路，它调控细胞的分化和增殖，在胚胎发育和细胞命运的决定中发挥重要的作用。

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The co-effect of extracellular-signal regulated kinase mitogen-activated protein kinase signaling pathway inhibitor and DNA methyltransferase inhibitor on human colon cancer cells

丝裂原激活蛋白激酶阻断剂与DNA甲基化酶抑制剂对人结肠癌细胞的协同影响

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Aim To investigate whether there is IL-12 signaling pathway through lck/ p38/ c-jun in splenic cells obtained from lupus mouse and its effect on splenic cells.

目的探讨在狼疮小鼠脾细胞中是否存在IL－12通过Lck／P38／c－jun传递信号及其对脾细胞的影响。

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It's very import to study the biosynthesis of endogenesis ethylene and ethylene signaling pathway.

乙烯生物合成的途径已经阐明，而乙烯信号转导系统的研究则刚刚起步，且主要集中在拟南芥上。

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Our results suggest the presence of an auxin signaling pathway that oppositely regulates growth and defense in the plant.

实验结果表明，存在一条生长素信号通路负向调控植物的生长而正向调控防卫。

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