osteoclast

Results: VEGF and CD34 were expressed in all cases of GCT investigated. VEGF was presented in spindle shaped stromal like tumor cells and osteoclast like multinucleate giant cells.

结果：VEGF在40例GCT中，无论是梭形的基质细胞，还是多核巨细胞均有表达，Ⅲ期的骨巨细胞瘤VEGF的表达明显高于第Ⅰ/Ⅱ期的GCT；

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influence of drynaria rhizome on culture in vitro of marrow osteoclast in rat

中药骨碎补对大鼠骨髓破骨细胞体外培养的影响

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Until now, the mechanism to control osteoclast division, growth, move and function and death is still not clear.

迄今为止，控制破骨细胞分化、成熟、迁移、发挥功能及凋亡的确切机制仍不清楚。

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Results Large multinucleated TRAP-positive osteoclasts from cortical bone were cultured. No obvious effect of icaritin on mature osteoclast was observed.

结果皮质骨内层可培养出多核、体积大、抗酒石酸酸性磷酸酶（TRAP）染色阳性的破骨细胞，淫羊藿提取物对皮质骨来源的破骨细胞没有明显影响。

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Osteoblast and osteoclast activity in a malignant infantile osteopetrosis patient following bone marrow transplantation.

骨髓移植之后的恶性婴儿骨硬化病的成骨细胞和破骨细胞活性.

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Conclusion: BYD could significantly inhibit the activity of osteoclast.

结论：补肾益精方具有明显的抑制破骨细胞活性的作用。

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Its differentiation effect on inhibiting osteoclast was assessed with statistics analysis.

统计学分析评价其抑制破骨细胞分化效果.

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Effects of Salvia Miltiorrhiza Bung on osteoclast like cells formation in mouse bone marrow culture

丹参对骨髓培养中破骨细胞生成的影响

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Object : The study a feasibility method of obtaining human osteoclast-like cells for purpose of further research.

目的: 探讨可行的获取人破骨细胞样细胞以供进一步研究的方法.

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Effects of combination of bone protectin and alendronate on differentiation of osteoclast precursors

联合应用骨保护素和阿伦膦酸钠对破骨前体细胞分化的影响

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CONCLUSION: RCMF can increase growth and excretory function of osteoblast and inhibit growth and function of osteoclast so as to elevate BMD and bone-loading forces, which has better interventional effect for osteoporosis.

结论：旋转恒定磁场能够促进大鼠成骨细胞的生长和分泌功能、抑制破骨细胞生长和破骨功能，从而提高骨密度及骨强度，对于骨质疏松有较好的干预效果。

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Frequent osteoclast-like giant cells are present.

常见破骨样巨细胞.

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Immunohistochemistry, the osteoclast-like giant cells were positive for CD 68. Vim, α1-ACT and negative for CK, EMA.

免疫表型: 破骨细胞样巨细胞CD68、Vim 、 α 1ACT 均阳性,ck 、 EMA均阴性.

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Bone resorptive function is resulting from the activation of osteoclast. Therefore, osteoclasts play a key role in bone formation and bone mass regulation.

骨吸收作用是通过破骨细胞的活动完成的，因此，破骨细胞在骨骼的形成和骨量的调节方面起着关键作用。

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The purified protein has been used for induced osteoclast differentiation in vitro.

纯化蛋白,体外诱导破骨细胞分化.

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NaF could directly injury osteoclast and inhibit bone resorptive function of osteoclast.

NaF可直接损伤破骨细胞并抑制破骨细胞的骨吸收能力。

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Conclusion Highly purified CD68+ cells can be obtained from human PBMCs as the osteoclast precursors, and mature osteoclasts can be induced from CD68+ mono/ macrophages by RANKL.

结论人外周血单核细胞中CD68+细胞是破骨前体细胞，在RANKL在诱导下分化为成熟破骨细胞。

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The experiments prove the establishment of the system can be trained induction of success with bone absorption function of the osteoclast.

证明本次实验建立的共培养体系可以成功诱导出具有骨吸收功能的OC。

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