oncogenic

Human papillomaviruses ( HPVs and herpes simplex virus type 2 ( HSV-2), both of which are oncogenic DNA viruses spread primarily by sexual contact, are closely associated with human cervical cancer.

人乳头瘤病毒（HPV）和人单纯疱疹病毒Ⅱ型（HSV-2）是与宫颈癌密切相关的丙种性传播DNA肿瘤病毒。二者皆可感染宫颈鳞状上皮细胞。

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Human papillomavirus is an oncogenic DNA virus and has more than 90 subtypes. High risk types ( HPV 16, 18, 33) are associated with many kinds of malignant neoplasms of head and neck.

人乳头状瘤病毒是一种致瘤性DNA病毒，在其90个亚型中以高危型HPV16，HPV18，HPV33等与人类头颈部恶性肿瘤关系密切。

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Ski plays multiple roles in a variety of cell types, it can induce both oncogenic transformation and terminal muscle differentiation when expressed at high levels.

Ski在各种细胞类型中发挥着不同的作用。Ski在细胞中的高表达可以诱导原癌细胞癌变和肌肉细胞终末分化。

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The results indicated that there was no oncogene in L783-MuLV genome, L783-MuLV belonged to slow oncogenic virus.

这说明，L783小鼠白血病病毒基因组中不含有致癌病毒基因，此病毒属于慢性致瘤性逆转录病毒。

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by contrast, the oncogenic variant spontaneously forms dimers that are constitutively active.

与此不同，致癌突变体自发形成有持续活性的二聚体。

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In addition to accumulating and preserving these oncogenic scars, a stem cell's enormous proliferative capacity makes it an ideal target for malignancy.

干细胞除了可累积并保存这些致癌突变外，还具有强大的增殖能力，使它成为癌化的理想目标。

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They are oncogenic DNA virus with icosahedral capsids 40 nm~ 45 nm in diameter, containing three to four viral proteins and double strand, covalently closed, circular genomes approximately 5 000 bp in size.

病毒无囊膜，直径40nm～45nm，有3种～4种衣壳蛋白，基因组为约5000对核苷酸组成的双链闭合环状DNA。

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Cerical cytology and biopsy were analyzed for 14 oncogenic HP types using polymerase chain reaction.

用聚合酶链反应分析了宫颈细胞学和活检中的14种致癌HP型.

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Moreover, it has been shown to induce steatosis, modulate apoptosis, and increase cellular oncogenic potential.

更且, 它会引起脂肪变性, 调节细胞凋亡, 增加细胞的致癌性.

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He assumed that the tumour cells, if they contained an oncogenic virus, should harbour viral DNA integrated into their genomes.

他认为，肿瘤细胞，如果它们载有致癌病毒，应港湾病毒DNA整合到它们的基因组。

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PGG could have repressed the transcription activity of oncogenic transcription factor NF-κ B to down-regulate the expression of apoptosis-inhibitory genes, finally triggered endogenous caspase apoptosis pathway death in ovarian cancer cells.

PGG可能通过抑制细胞内致癌转录因子NF-κB的活性，下调其凋亡抑制基因的表达，诱导细胞进入内源性Caspase凋亡途径，从而导致细胞死亡。

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