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Methods: The 68 patients meeting criteria of manic episode or schizoaffective disorder in CCMD-3 were randomly divided into studying group ( combination of quetiapine and lithium or valproate) and control group ( single using of lithium or valproate) and observed for 6 weeks.

方法将符合CCMD-3躁狂发作或分裂情感障碍诊断标准的68例研究对象随机分成两组,研究组应用奎硫平合并碳酸锂或丙戊酸钠,对照组单一使用碳酸锂或丙戊酸钠,治疗观察6周。

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A comparative study of lithium carbonate combined with sodium valproate in the prevention of bipolar disorder

碳酸锂合并丙戊酸钠预防双相障碍复发的研究

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METHODS: Sodium valproate was administered by osmotic minipump technique ( 1. 062 mg · h-1) and iv ( 50 mg · kg-1) to ICR mice fed under ad lib or time-restricted schedules to determine the time-dependent changes of VA kinetics.

方法:对自由进食及限定进食的ICR小鼠分别以渗透压微泵技术(1.062mg·h~(-1))及iv(50mg·kg~(-1))给予丙戊酸钠,并测定VA动力学的时间依赖性变化。

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RESULTS: Simple and complex partial seizures with or without secondary generalized seizure, in topiramate group were much more improved than these in sodium valproate group 6 mo after treatment.

结果:托吡酯组治疗6mo的继发性全身发作,简单及复杂性部分发作有效例数优于丙戊酸钠组,4例在加药期快时出现疲劳、嗜睡、注意力不集中等。

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Proliferation inhibition of sodium valproate on lung cancer cell line A549

丙戊酸钠抑制肺癌细胞株A549增殖的研究

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Research group were given anti-psychotics combined with magnesium valproate, its beginning dosage was 400mg/ d and reached 800~ 1200mg/ d after one week, and control group with single anti-psychotics for 4 weeks.

研究组在原有抗精神病药治疗的同时加用丙戊酸镁治疗,起始剂量400mg·d-1,1w后增至800mg~1200mg·d-1;对照组继续原有抗精神病药治疗。

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since 2004, prescriptions of carbamazepine, phenytoin and valproate decreased while levetiracetam increased.

从2004年,卡马西平、苯妥英和丙戊酸盐的剂量减少了然而左乙拉西坦的剂量增加了。

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objective: to study and compare the prophylactic efficacy of levetiracetam, valproate and phenobarbital on febrile convulsions in rats.

目的:比较左乙拉西坦、丙戊酸钠、苯巴比妥对大鼠反复热性惊厥的预防作用的差异,指导临床选药。

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a case of acute interstitial nephritis caused by sodium valproate is reported.

例急性间质性肾炎造成丙戊酸钠报道。

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a clinical contrast of curative effect of topiramate and sodium valproate in treatment of general tonic clonic seizure

托吡酯和丙戊酸钠治疗特发性全面性强直阵挛发作的临床疗效比较

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an analysis of the result from monitoring serum concentration of children with epilepsies treated with sodium valproate

丙戊酸钠治疗儿童癫痫的血药浓度监测结果分析

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clinical analysis of antiepileptic therapy with individuated-dose valproate in child

丙戊酸钠个体化剂量治疗癫痫的临床分析

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sodium valproate effectively protected against stage 5 seizures and shortened the afterdischarge duration.

丙戊酸钠抑制5期反应作用较强,并能显著缩短刺激后放电时程。

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15、

results: the rate effective cure for primary trigeminal neuralgia with sodium valproate was 79.5% and effective daily dose was 0.6~ 2.0g.

结果丙戊酸钠治疗原发性三叉神经痛的总有效率为79.5%,剂量为0.6~2.0g。

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16、

effects of sodium valproate on electrocardiographic changes and death time in rats

丙戊酸钠对小鼠心电改变及死亡时间的影响

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importance of monitoring of serum concentration of sodium valproate in epileptic children

血药浓度监测对丙戊酸钠治疗小儿癫痫的指导意义

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18、

pharmacokinetics of sustained-release sodium valproate in 5 children with epilepsy

丙戊酸钠缓释片在5例癫痫儿童的药物动力学

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effect of sodium valproate on ectopic spontaneous discharge of injured dorsal root ganglion neurons in rats

丙戊酸钠对大鼠损伤背根节神经元异位自发放电的抑制作用

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Clinical analysis of thrombocytopenic purpura caused by sodium valproate treatment in 8 children with epilepsy

丙戊酸钠致血小板减少性紫癜8例临床分析

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