1、

The rosuvastatin with Losartan group compared with ox-LDL group-、 rosuvastatin group 、 Losartan group the expression of TF mRNA decreased and this was in a concentration-dependent fashion ( P0.05).

瑞舒伐他汀联合氯沙坦组与ox-LDL组、瑞舒伐他汀组、氯沙坦组比较Tf mRNA和蛋白的表达减少,差异具有统计学意义(P0.05)。

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2、

The electrospray ionization-mass spectrometry result showed that it was an isomeric compound of losartan, which had same fragmentation pattern with its parent ( compound).

质谱分析结果表明,该杂质的相对分子质量与洛沙坦的相同,质谱裂解规律与洛沙坦一致;

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3、

The treated group with conventional medicine plus Losartan and Simvastin ( D group).

常规治疗+氯沙坦+辛伐他汀治疗组(D组),同时设20例健康对照组(E组)。

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4、

Effect of losartan on urinary podocyte excretion in diabetic nephropathy patients

氯沙坦对糖尿病肾病患者尿足细胞排泄的影响

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5、

Effect of Spironolactone and Losartan on Myocardium Collagen in Rats with myocardial Infarction

大鼠心肌梗死后螺内酯与氯沙坦干预对其心肌胶原变化的影响

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6、

Conclusion Losartan potassium and amlodipine together can lower blood pressure, pulse pressure and the concentration of blood uric acid, and improve the function of kidney.

结论氯沙坦钾与氨氯地平联合用药能有效降低血压,缩小脉压差,降低血尿酸浓度,改善肾功能。

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7、

Results Both irbesartan and losartan were effective for lowering blood pressure. 80.6% and 82.6% of the patients in each group were considered to improve in 8 weeks with no significant difference statistically between the two groups.

结果厄贝沙坦与氯沙坦均能有效降低血压,治疗总有效率分别为85.6%和82.6%(P>0.05),两组降压程度无统计学意义(P>0.05)。

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8、

Objective To observe the effects of Losartan on the level of serum and urinary intercellular adhesion molecule-1 ( ICAM-1) in patients with incipient Diabetic nephropathy ( IDN).

目的观察氯沙坦对早期糖尿病肾病(IDN)患者血清、尿液细胞间粘附分子-1(ICAM-1)水平的影响。

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9、

Methods 48 patients with IDN ( without hypertension) were randomly divided into 2 groups, one group took Losartan 50 mg daily with the treatment of blood glucose lowering for 4 weeks, and the other only with blood glucose lowering;

方法48例IDN(不伴高血压)患者随机分为两组,一组仅降血糖治疗,另一组联合服用氯沙坦50mg/d,共观察4周;

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10、

The two antihypertensive drugs are characteristics of specific receptor, medication safety, well-tolerated, significant antihypertensive effect, lower side effect.5-carboxylic acid Losartan ( EXP-3174) is the active metabolite of Losartan.

这两种降糖药具有受体作用的专一性,用药安全,耐受性良好,抗高血压作用显著,副作用小的特点。5-羧酸洛沙坦(EXP-3174)是洛沙坦的活性代谢产物。

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11、

Objective To explore the mechanism of action of Losartan on vascular remodelling in hypertension and its relationship with neuroendocrine factor and renin-angiotensin system.

【目的】探讨洛沙坦(Losartan)对高血压病人血管重塑的作用机制以及肾素血管紧张素系统和神经肽Y(NPY)在高血压、动脉粥样硬化等心血管疾病发生的作用。

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12、

Effect of losartan and perindopril on hyperglycemia inducing transdifferentiation in NRK-52E

氯沙坦及培哚普利对高糖诱导NRK-52E细胞转分化作用研究

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13、

the first involves the use of the drugs lisinopril, carvedilol, spironolactone, and losartan to enhance reverse remodelling.

第一个阶段包括药物赖诺普利,卡维地洛、螺内酯和洛沙坦的应用,以提高逆转重塑。

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14、

comparative study on effect of losartan and lisinopril in patients with hypertension and hyperuricemia

氯沙坦和赖诺普利治疗高血压合并高尿酸血症的比较

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15、

myocardial hypertrophy in pressure overload rats and the preventive effects of losartan and lisinopril

大鼠压力负荷性心肌肥厚与氯沙坦及赖诺普利的预防作用

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16、

effects of treating uricacidemia by losartan in patients with hypertension associated hyperuricemia

氯沙坦治疗高血压合并高尿酸血症疗效的临床观察

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17、

objective by observing degree of myocardial fibrosis, changes of vascular endothelium dependent relaxation dysfunction of elderly rats and losartan's intervention effect, to explore the protective effect of angiotensin ii receptor i antagonist on cardiac and arterial aging.

目的观察老龄大鼠心肌纤维化程度、血管内皮依赖性舒张功能不全的变化及洛沙坦的干预作用,探讨血管紧张素II受体I(AT1R)拮抗剂(ARB)对心脏和动脉衰老的保护作用。

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18、

conclusions losartan alleviates tnbs-induced pancreatic fibrosis in rats, suggesting that rennin-angiotensin system might be one of the important contributors for formation of pancreatic fibrosis.

结论1型血管紧张素Ⅱ受体拮抗剂对TNBS诱导的大鼠胰腺纤维化形成具有抑制作用,表明肾素血管紧张素系统(RAS)在慢性胰腺炎胰腺纤维化的发生发展过程中起重要的介导调节作用。

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19、
20、

Regression of Hypertrophy of Coronary Arteries in SHR After Low and High Dose Losartan Treatment

不同剂量罗沙坦对高血压大鼠冠状动脉壁肥厚的逆转作用

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