1、

Alkylation of imines can be applied to the synthesis of various useful compounds and aza-Diels-Alder reaction can yield not only optically active but also sterically constrained α-amino acid derivatives. This paper just have a simple introduction and a discussion on both of these reactions.

亚胺的烷基化反应能用来合成大量的化合物,而aza Diels Alder反应[1]不仅可以合成有空间位阻的,而且能合成具有光学活性的α氨基酸衍生物。

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2、

Azathioprine ( AZA) and 6-mercaptopurine ( 6-MP) have a well-established effect as an immunosuppressive agent for inflammatory bowel disease ( IBD), Myelosuppression is the most serious side effect during treatment.

硫唑嘌呤(AZA)/6-巯嘌呤(6-MP)是治疗炎性肠病(IBD)的重要药物,治疗过程中最严重的不良反应是骨髓抑制。

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3、

Effects of DNA methyltransferase activity in lung cancer cells treated with 5-Aza-CdR

5-Aza-CdR对肺癌A549细胞DNA甲基转移酶活性的影响

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4、

BACKGROUND& OBJECTIVE: 5-Aza-2 ′-deoxycytidine ( 5-Aza-CdR) is an inhibitor of DNA methyltransferase; it may reactivate methylated antioncogene, therefore, inhibit the growth of cancer cells.

背景与目的:5-杂氮-2′-脱氧胞苷是DNA甲基转移酶抑制剂,能使因甲基化而失活的抑癌基因重新激活,进而抑制肿瘤的生长。

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5、

Methods To investigate the changes of DNA methyltransferase 1 ( DNMT_1) mRNA and methylation status of progesterone receptor double promotors ( PRA, PRB) before and after 5-Aza-2 ′-deoxycytidine treatment.

方法用5-杂氮-2′-脱氧胞苷处理白血病细胞株HL-60、K562和Jukat,分析处理前后DNA甲基转移酶1mRNA表达和孕酮受体双启动子(PRA、PRB)甲基化状态的变化。

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6、

This review deals with the development of bifunc-tional reagents in synthesis of aza-crown compounds.

综述了氮杂冠醚合成中的双功能基试剂的进展.

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7、

before and after cryopreservation, the cells showed ctn -i positive after 28-day induction by the 5-aza.

冻存前后脂肪间充质干细胞经5-氮杂胞普诱导后第28天时心肌特异性肌钙蛋白-I均呈阳性表达。

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8、

objective to explore the effect of 5-aza-2 ′ deoxycytidine on the growth of cne cell line and find new target of nasopharyngeal carcinoma therapy.

目的探讨5-杂氮-2′-脱氧胞苷(5-Aza-CdR)抑制人鼻咽癌CNE细胞系生长增殖的机制,寻找鼻咽癌治疗的新靶点。

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9、

Besides, the synthesis of diphenyl ether, diphenyl oxadiazole diphenyl amine and aza-bis ( oxazolines ) is also discussed.

另外, 还讨论了苯甲醚类 、 二联苯恶二唑类、联苯胺类与 氮杂 类等新型双恶唑啉配体的合成.

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10、

The expression of RASSF 1 A protein increased with the doses of 5-Aza-CdR.

荧光显微镜下见典型的凋亡形态学改变,随5-Aza-CdR浓度的升高 BIU87 细胞RASSF1A蛋白的表达也升高.

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11、

The regimen of treatment after retransplantation was Pred + Aza ( 16 cases ) 、 CsA + Pred + Aza ( 33 cases ), CsA + Pred + Aza + ALG ( 13 cases ), CsA + Pred + Aza + ATG ( 5 cases ).

再次移植用药方案:Pred+Aza ( 16例 ),CsA+Pred+Aza ( 33例 ),CsA+Pred+Aza+ALG ( 13例 ), CsA+Pred+Aza+ATG ( 5例 ),6个月肾存活分别为43.8% 、 54.5%、92.3%、80.0%.

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12、

The calculated results show that the aza Wittig reaction is a two step reaction, having one four membered ring intermediate on its reaction surface.

计算结果表明该反应是一个二步反应,在反应途径上存在一个四元环中间体。

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13、

A film forming quarternary ammonium salt corrosion inhibitor 9912 1 containing aza heterocycle was synthesized.

设计合成了一种成膜型的氮杂环的季胺盐缓蚀剂99121。

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14、

This thesis describes the syntheses and complexation properties of some novel calixarene aza derivatives and polymers.

为此,本论文设计并合成了在下沿同时引入多个含氮的软配位基团的杯芳烃衍生物及其聚合物。

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15、

These findings show Aza toxic reaction, especially the liver toxicity is significant, much attention should be paid.

结果说明Aza的毒性反应尤其是肝毒性仍很明显。

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16、

The incidence of liver function damage and infections in MMF group is lower than that in AZA group.

MMF组肝功能损害和感染的发生率均较AZA组低。

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17、

CONCLUSION The optimal condition to make the acute hepatic injury model induced by AZA in mice are administrated 150 mg/ kg AZA and treated for 12 hours.

[结论]利用AZA制作急性肝组织损伤小鼠模型时,AZA的最佳给药剂量为150mg/kg,最佳作用时间为给药后12h。

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18、

The Aza-Wittig Reaction in Heterocyclic Synthesis

杂环合成中的氮杂Wittig反应

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19、

T_ ( 11) and Aza were similar in suppressing immune respone.

雷公藤多甙与硫唑嘌呤的免疫抑制作用强度相似。

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20、

Role of thiopurine methyltransferase measurement prior to treatment of IBD with AZA/ 6-MP

硫唑嘌呤/6-巯嘌呤治疗炎性肠病前检测硫嘌呤甲基转移酶的临床意义

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