2、

STZ induced diabetic rat is a reliable animal model which can be used to imitate human nonproliferation diabetic retinopathy. 2.

结论1.STZ诱导的糖尿病大鼠,是模拟人非增殖期糖尿病视网膜病变的一种可靠的动物模型。

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There was no significant difference between STZ glyburide group and STZ insulin group, neither between STZ glyburide group and STZ lipectomy group ( P> 0.05).

胰岛素组与格列本脲组,以及手术组与格列本脲组之间比较,差异无显著性意义(P>0.05)。

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Results: Pue has little influence on fasting blood glucose of normal mice, but can lower blood sugar and serum insulin of diabetic mice by STZ induced and increase insulin sensitivity index significantly as well as improve IR by HCSS induced significantly.

结果:Pue对正常小鼠空腹血糖无明显影响,可明显降低STZ诱导的糖尿病小鼠的血糖和血清胰岛素含量,使胰岛素敏感性指数显著升高,对HCSS诱导的IR也有明显的改善;

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Establishment of STZ-Induced Diabetic Nephropathic Rat Model

STZ诱导糖尿病肾病大鼠模型的建立

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The rats were fed with the diets: high sucrose and fat, cholesterol and cholate in a month, getting intra-abdominal injection of STZ 45mg/ kg to make the models of DM macrovascular disease established.

通过高糖、高脂、胆固醇、胆酸盐等膳食方法喂饲一个月及腹腔注射链脲佐菌素(STZ)45mg/kg,复制糖尿病大鼠大血管病的病理模型。

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Conclusions The accumulation of glomerular extracellular matrix which leads to mesangial expansion and glomerular hypertrophy can be completely prevented by 12 week C peptide treatment independent of metabolic control in STZ rats. But there is no prevention effect on whole kidney hypertrophy and leakage of urinary albumin.

结论单独应用C肽12周可以预防STZ大鼠肾小球细胞外基质积聚导致的系膜扩张和肾小球肥大,且不依赖糖代谢紊乱的纠正,但对整个肾脏肥大和尿白蛋白漏出没有预防作用。

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Conclusion: DC has obvious anti-hyperglycemic effects in adrenaline-induced hyperglycemic mice and STZ-DM rats.

结论:铁皮石斛对肾上腺素性高血糖小鼠及STZ DM大鼠有明显的降血糖作用。

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【 Conclusion 】 In the present study, STZ successfully induced non-insulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus models.

【结论】本研究用100mg/kg和160mg/kg的STZ成功诱导了非胰岛素依赖性糖尿病模型和胰岛素依赖性糖尿病模型。

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The effect of methylcobalamin on the secretion of testosterone in STZ induced diabetic rats

甲基维生素B(12)对链脲佐菌素诱导的糖尿病大鼠睾酮分泌功能的影响

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STZ is one of the classic diabetes inducers, characterized by selectively and directly impairing DNA of β cell which caused by its alive hydrocarbyl; then the antigen of β cell released which consequently processed and presented to T lymphocyte by macrophage.

STZ是经典的致糖尿病药物,具有活泼的烃基结构,可以选择性地直接损伤胰岛β细胞DNA,使β细胞抗原释出并被巨噬细胞加工、呈递给T淋巴细胞,引起免疫应答反应;

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Hypoglycemic effect of bovine colostrum truncated IGF-1 in STZ-induced diabetic rats

牛初乳短链IGF-1对STZ诱导糖尿病大鼠的即时降糖作用观察

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Objective: To study the anti hyperglycemic effect of rubusoside on diabetic rats induced by streptozotocin ( STZ) and its mechanism.

目的:研究甜茶素提取物对STZ致高血糖大鼠的降血糖效果及其降糖机制。

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Change of lens were recorded weekly by using slit lamp microscope camera during STZ model group, SM eyedrop group and contrast group.

实验分为STZ模型组、丹参滴眼组和空白对照组,每周裂隙灯显微镜照相机记录晶状体变化。

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Express of TGF-β_1 and ECM in STZ Diabetes Rats

糖尿病大鼠肾组织TGF-β1及细胞外基质表达

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Relationship between apoptosis and retinal microvascular pathological changes in STZ diabetic rats

细胞凋亡与STZ糖尿病大鼠视网膜微血管病变关系

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The model was established through injection with streptozotocin ( STZ).

B组和C组通过腹腔注射链脲佐菌素(Streptozocin,STZ)建立糖尿病模型。

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· METHODS: Diabetes was induced by intraperitoneal injection of STZ.

方法:腹腔注射链脲左菌素(STZ)来诱导糖尿病。

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Evaluation of experimental animal model of diabetic retinopathy induced by STZ rat

STZ糖尿病大鼠视网膜病变模型的评价

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Conclusions Consistent diabetic hamster models can be established by intraperitoneal injection of STZ.

结论腹腔注射STZ可诱导稳定的糖尿病仓鼠动物模型;

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