they are like flowers in the greenhouse, not a desert rose, according to the sun to dry out.

the pair then went on to form the desert rose band, one of the most popular country music bands of the late 1980's and '90s.

两人接着形成沙漠玫瑰乐队，一个最流行的1980年国家的乐队后期和90年代。

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in tunisia , many places sell the desert rose gift shop, desert rose seems to have become the characteristics of cultural symbols tunisia .

在突尼斯，很多地方都有卖沙漠玫瑰的礼品店，沙漠玫瑰俨然成了突尼斯的特色文化符号。

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sonorous description: when this charm is cast upon someone 's throat , their voice will magnify to carry over a large crowd .

当此咒语被释放到某人的喉咙上时，该人的嗓音将被放大到能传递到一大群人中。

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our eyes have the capacity to magnify to perceive close up or pan back to see the distance at will, much like your cameras in human form.

我们的眼睛能任意放大或缩小，来观察就近或远处的事物，就像你们人类的照相机。

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it tends to magnify, to an unusual degree, human managerial talent - or the lack of it.

保险趋向于以非常大的比例放大管理人才（或者缺乏管理人才）的效果。

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the protein folding problem has two components: the direct folding problem ( i.e. folding) and the inverse problem ( i.e. protein design).

蛋白质折叠问题包含两个方面的内容：正折叠问题（称为蛋白质折叠）和逆折叠问题（即蛋白质设计）。

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although researches on the protein structures got more and more attention because they are the foundation of the function research and protein design, the experiment of protein structural determination is quite time-and money-consuming and of limited success rate.

所以蛋白质结构的研究是功能研究和蛋白质设计的基础，也因此越来越得到重视。蛋白质种类繁多，结构千差万别，同时蛋白质结构测定实验是非常费时费力，消耗资源也大，而且成功率有限。

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the development of protein therapeutics and research of protein interaction networks require selective protein inhibitors and design of function and property of proteins.

对蛋白质及其相互作用等网络的进一步深入研究将会有越来越多对特异性蛋白抑制剂以及蛋白质功能和特性进行改造的需求；

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conclusion: high expression of scf-tpo fusion protein has been obtained and protein prediction shows that the fusion protein design is reasonable, which lay foundation for further study of biological fundation of scf-tpo fusion protein.

结论：获得了SCF-TPO融合蛋白的高表达，结构预测融合蛋白的设计符合要求。为进一步研究SCF-TPO融合蛋白的生物学特性奠定了基础。

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understanding this mechanism would greatly accelerate our study on the protein self-assembling, and moreover, be helpful to protein design and to the treatment of various diseases relevant to protein misfolding ( such as mad cow disease and alzheimer disease).

了解该机制将加深我们对蛋白质自组装过程的认识，进而为治疗各种蛋白质折叠病（如疯牛病和老年痴呆症）提供帮助，为蛋白质分子设计提供指导。

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research of protein folding becomes the core subject related to protein design and molecular biology.

蛋白质折叠相关研究对蛋白质设计、疾病成因等方面研究有决定作用，已经成为众多相关学科研究中的核心问题。

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it plays a very important role in gene discovery, genetic diagnosis of diseases, prediction of protein structure, drug design based on molecular structure, drug synthesis and pharmaceutical industry. the application of bioinformatics has greatly quickened the speed of drug exploitation.

生物信息学在基因发现、疾病基因诊断、蛋白质结构预测、基于结构的药物设计、药物合成和制药工业中起着极其重要的作用，生物信息学的应用大大加快了药物的研究开发进程。

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alternatively, investigators might analyze the three-dimensional structure of a protein domain and then design drugs that bind tightly to that region.

或者，研究人员也可以分析某个蛋白质区间的立体构造，设计出与该区间紧密结合的药物。

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theoretical study of protein folding and protein design based on the relative entropy and complex network methods

基于相对熵和复杂网络方法的蛋白质折叠与设计理论研究

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methods: the protein molecule design included truncation at n_terminal, replacement of basic amino acid and reduction of the number of cysteine.

方法：分子改造包括以下内容：分子截短，突变碱性氨基酸，减少半胱氨酸的数目等。

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study of linear neutralizing epitopes of hepatitis e virus capsid protein and design and construction of epitope-based vaccine

戊型肝炎病毒衣壳蛋白的线性中和性表位的研究及其一种表位疫苗的设计与构建

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we introduced local interaction optimization in protein functional design, which is to optimize every local interaction between the protein and the ligand.

我们这里采取另外一种策略，即优化蛋白质和小分子之间的每个局部相互作用。

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it is an important issue in protein functional design.

特异性界面的设计是蛋白质功能性设计的主要问题之一。

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in order to overcome the difficulty of applying dual monte carlo method to the bigger molecule system and off-lattice model, a simple new method of protein design based on relative entropy is proposed.

为了克服双重蒙特卡罗方法用于较大分子体系及非格子模型的困难，提出了一个基于相对熵的蛋白质设计的简单方法。

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structural bioinformatics based rational protein design will play important role in biological research and development of protein therapeutics in the post genome era.

利用结构生物信息学方法进行蛋白质的理性设计，将会在后基因组时代的生物学研究和蛋白药物开发中起到越来越重要的作用。

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