pharmacophore perception, development, and use in drug design

1、

constructing the pharmacophore models of tyrosinase inhibitors by disco method

距离比较法构建酪氨酸酶抑制剂的药效团模型

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2、

using distance comparison method to build pharmacophore model of epidermal growth factor receptor inhibitors

距离比较法构建表皮生长因子受体抑制剂的药效团模型

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3、

a three-dimensional pharmacophore model of two types of her2 inhibitors was obtained by using the catalyst software.

通过CATALYST软件包得到了两类HER2抑制的三维药效团模型。

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4、

this is because once a pharmacophore is known, medicinal chemists can modify it to reduce toxicity while maintaining (or enhancing) potency.

这是因为一旦知道药效基因，药物化学家就可以修饰它，在保持药效的基础上减少毒性。

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5、

moreover, development of pharmacophore point theory greatly increases the effectivity of virtual screening in the database.

而且，药效团模型理论的发展大大提高了在数据库中进行虚拟筛选的有效性。

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6、

recent reviews in drug discovery today have concentrated on screening by docking and by pharmacophore searching.

最近的评论今天在药物发现都集中在筛选对接和药效搜索。

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7、

the experiment proves that the derivative plays better medicine effect than single pharmacophore.

实验证明这种衍生物的药效比单一的药效基团发挥的更好。

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8、

research of servo system mechanical resonance

伺服系统机械谐振问题的研究

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9、

the effect of the mechanical resonance and compensation method in cnc heavy cutting

数控强力切削中机械谐振的影响及补偿方法

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10、

effective suppression of mechanical resonance to provide a stable control system

有效抑制机械共振，提供控制系统稳定性

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11、

an improved digital filter for restraining mechanical resonance frequency

抑制机械谐振的一种改进的数字滤波器

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12、

simulated analysis of ground-water seepage field in anqing copper mine

安庆铜矿地下水渗流场的模拟

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13、

plant unit 5, 6 low-e were found in ground water seepage.

6号机组厂房亦发现有低辐射地下水渗出。

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14、

special stamping of combination units

组合设备的特殊标志

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15、

but on wednesday (feb 16), the airport council international announced its 2010 airport service quality awards.

不过在2月16日，国际机场协会（AirportCouncilInternational）还是如期宣布了2010年度机场服务质量奖（2010AirportServiceQualityAwards）。

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16、

experiences of applying on-line banking system for payment in huzhou electric power company

湖州电力局实施银行实时联网缴费系统的几点体会

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17、

on-line banking system in which the technical program to do an in-depth description.

其中对网上银行系统的技术方案做了深入的描述。

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18、

of what use is it to have many irons in the fire if the fire is going out?

如果火都快熄灭了，加一堆烙铁有甚么用呢？

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19、

using the range operator in wildcard queries

在通配符中使用范围运算符

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20、

it can include the range operator (a colon), the intersection operator (a space), or the union operator (a comma).

范围名称可以包括范围运算符（冒号）、交集运算符（空格）或并集运算符（逗号）。

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