Effects of glycine on the ATP depletion-induced autophagy in MDCK cells

Although autophagy has long been viewed as a random cytoplasmic degradation system, the involvement of ubiquitin as a specificity factor for selective autophagy is rapidly emerging.

虽然，细胞自噬长期以来被视作为一种随机的细胞质降解体系，但是泛素的参与作用作为一种选择性细胞自噬的特异性因子的观点，正在迅速崛起。

互联网摘选

Conclusion The loss of the ability of differentiation and epithelial formation and the harvest of the capability of brooding from former plasmalemma 'nutshell' of original epithelial cells might be the typically morphological characteristics of the dedifferentiated basal cells in PEH.

结论在PEH组织中丧失分化和表皮结构形成能力的表皮基底细胞呈脱壳样与原细胞浆膜结构分离，是基底细胞去分化的典型形态特征。

互联网摘选

KIM-1 is specifically expressed by dedifferentiated renal tubular epithelial cells, suggesting that it may contribute to dedifferentiation, proliferation, migration, and continuous reconstruction of renal tubular epithelial cells.

KIM-1在去分化肾小管上皮细胞的特异性表达提示可能参与肾小管上皮细胞的去分化、增殖、迁移，促进上皮细胞连续性的重建。

互联网摘选

Autograft peripheral nerves can regulate gene expressions in macroglia cells and induce the dedifferentiation of macroglia cells in the optic nerve.

移植周围神经改善了视神经损伤后抑制性微环境，影响胶质细胞基因表达，并诱导大胶质细胞去分化。

互联网摘选

BACKGROUND: In cartilage tissue engineering, chondrocytes cultured in vitro expansion of are prone to dedifferentiation, with the characteristic of disappeared cell phenotype, reduced ability of synthesis of extracellular matrix.

背景：软骨组织工程中，体外扩增的软骨细胞极易发生去分化，表现为细胞表型消失，合成细胞外基质能力下降。

互联网摘选

Furthermore, AE anticancer activities was associated with downregulation expression of methionine adenosyltransferase II which promote cell growth and dedifferentiation.

苹果提取物还可能通过抑制与细胞的生长、去分化和癌症有关的甲硫氨酸腺苷基转移酶Ⅱ的表达发挥抗肿瘤作用。

互联网摘选

It is well known that the incomplete dedifferentiation and reprogramming of donor nuclei in the oocytes-cytoplasm is the main factors leading to low efficiency in nuclear transfer.

目前普遍认为，核移植效率低主要是由于供体细胞核在卵母细胞中的去分化和重编程不完全。

互联网摘选

It suggests that epidermal cells occur dedifferentiation to promote wound repair of skin in some conditions. 4.

在皮肤创伤修复过程中，一定条件下表皮细胞可能发生去分化，从而促进创伤修复。

互联网摘选

Objective To investigate the roles of mouse erythroid differentiation and denucleation factor ( MEDDF), newly cloned in our laboratory, in erythroid terminal differentiation.

研究小鼠红细胞分化去核分化因子（MEDDF）在红细胞终末分化中的功能。

互联网摘选

To study the effects of IGF-I on the tendency of growth and de-differentiation of the three-cultured chondrocytes, in order to gain large amount of good type chondrocytes.

研究了解胰岛素样生长因子Ⅰ（IGF-I）对三维培养条件下关节软骨细胞生长和去分化趋势等生物学行为的影响，以期获得大规模生物学性状良好的软骨细胞。

互联网摘选

Gains and Lose Lose Heaven ( 2) The chondrocytes differentiate and lose their special phenotypes gradually with passage.

随着传代培养次数的增加，骺板细胞出现去分化，逐渐失去软骨细胞的特异性表型。

互联网摘选

In addition, silk fibroin has good biocompatibility. It can inhibit cartilage differentiation of cartilage cells.

此外，丝素蛋白是一种生物相容性较好的生物材料，在抑制软骨软骨细胞的去分化方面具有很好的效果。

互联网摘选

Carcinogenesis of primary liver tumor has ever been attributed to dedifferentiation of mature cells; however, recent studies hold that it might be caused by disdifferentiation of hepatic stem cell ( HSC).

原发性肝癌的发生曾归因于成熟细胞的去分化（dedifferentiation），但是，近年来研究认为它可能由肝干细胞（Hepatic stem cell，HSC）分化不全或分化异常（disdifferentiation）所致。

互联网摘选

Conclusion The expressive products of c jun gene was important for VSMC to keep dedifferentiated.

提示C JUN基因表达产物在维持血管平滑肌细胞于去分化状态中起重要作用。

互联网摘选

[ Conclusion] The proliferation of dedifferentiated parietal cells and the reconstruction of oxyntic gland are the histological characteristic of ulcer total healing.

[结论]壁细胞去分化增殖、再分化重构泌酸腺，是胃体溃疡完全愈合的组织学特征。

互联网摘选

The dedifferentiation phenomenon of epidermal cells is approved by the study of animal model of epidermic grafting with eliminating basal layer of epidermis.

在去表皮基底层表皮皮片移植到裸鼠的动物实验模型研究中进一步证实了表皮细胞去分化这一生物学现象存在的可靠性。

互联网摘选

Role of Autophagy in Dedifferentiation of Schwann Cells after Transection of Rat Sciatic Nerve

自噬在大鼠坐骨神经横切后施万细胞去分化中的作用

互联网摘选

Updated Dedifferentiation and Pluripotency of Spermatogonial Stem Cells

精原干细胞去分化和多能性的研究进展

互联网摘选

Experimental study of human adipocyte dedifferentiation for adipose tissue engineering

脂肪细胞去分化及构建组织工程化脂肪的实验研究

互联网摘选

Knockdown of Blimp-1 expression results in plasma cell dedifferentiation

抑制Blimp-1表达导致浆细胞去分化

互联网摘选