METHOD Nefiracetam was synthesized by N acylation of2,6 dimethylbenzenamine with chloroacetylchloride and N alkylation of2 pyrrolidone.

  • 方法以2,6二甲基苯胺为起始原料,经氯乙酰氯N酰化反应和2吡咯烷酮的N烷基化反应合成了奈非西坦。
  • 来源:互联网摘选更新时间:2026-07-13 20:04:11

  • 重点词汇
  • wasv. 用来表示某人或某物即主语本身,用来表示某人或某物属于某一群体或有某种性质( be的过去式 );在,存在;不受干扰;
  • synthesizedv.综合( synthesize的过去式和过去分词 );人工合成;(通过化学手段或生物过程)合成;(音响)合成;
  • nn. 英语字母表的第14个字母;表示不定数
  • 6num. six;
  • andconj. 和;与;而且;于是;然后
  • 相关例句
1、

Influence of Catalysts Particle Size on Alkylation of Isobutane with Butene over H β Zeolites

Hβ沸石粒度对异丁烷与丁烯烷基化反应活性和选择性的影响

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2、

Side chain alkylation of p-xylene with methanol on modified X type zeolites

对二甲苯与甲醇在改性X型沸石上的侧链烷基化反应

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3、

Alkylation of benzene with propene over H β zeolite modified with citric acid

柠檬酸改性Hβ分子筛上的苯与丙烯烷基化反应

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4、

Catalytic N-Alkylation of Amides with Polystyrene Supported Polyethylene Glycols

聚苯乙烯固载聚乙二醇催化酰胺的N-烷基化反应

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5、

Synthesis of 4-( N, N-diallylamino) pyridine by Na-substitution N-alkylation

钠取代N-烷基化反应合成4-(N,N-二烯丙基氨基)吡啶

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6、

Studies of Phase Transfer Catalysis for N-Alkylation of 2-Methylindole

相转移催化2-甲基吲哚的N-烷基化反应

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7、

Alkylation studies of Isobutane with c_4 olefins

异丁烷与C4烯烃烷基化反应机理的研究及进展

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8、

Alkylation of Toluene with tert-Butyl Alcohol over H Type Mordenite Catalyst

H型丝光沸石催化剂催化甲苯与叔丁醇的烷基化反应

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9、

The study was made of gas N alkylation of aniline and alcohol in fixed bed reactor.

用固定床反应器对苯胺和醇类气相N烷基化反应进行了研究。

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10、

We explored the mechanism of the C alkylation between 5-chloromethyl-8-hydroxyquinoline and aromatic amines.

3对5-氯甲基-8-羟基喹啉与芳胺C烷基化反应的机理进行研究。

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11、

Seven new β-DDB derivatives were prepared from gallic acid in 9 steps such as Ullmann coupling reaction, alkylation, benzoylation etc. The structures of these compounds were identified by(()~ 1HNMR.)

以没食子酸为原料,通过Ullmann偶合反应、烷基化、酰基化等9步反应合成了7种-βDDB的衍生物,其结构经1HNMR确认。

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12、

This chapter was using different synthetic strategies to obtain target ligand: A is by Friedel Crafts acylation reaction followed by Mcmurry reaction; B is by classical Suzuki coupling reaction.

本章分别采用不同的合成策略得到目标配体:A是经付克酰基化与迈克摩尔反应;B是选用Suzuki偶合反应。

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13、

Firstly the intermediate 2-( 2-hydroxyphenyl) phenylphosphinic acid ( HPPA) was prepared in 92.5% yield through continuous esterification, acylation and hydrolysis.

首先将酯化、酰基化、水解反应连续进行,得到了中间体2-(2-羟基苯基)苯基膦酸(HPPA),收率92.5%。

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14、

As an intermediate for COX-2 inhibiters, 4-( methylthio) benzeneacetic acid(ⅳ) was prepared via Friedel-Crafts and Willgerodt-Kindler reaction from thioanisole(ⅰ).

以茴香硫醚(Ⅰ)为原料,经Friedel-Crafts酰基化、Willgerodt-Kindler反应合成了COX-2抑制剂的中间体4-甲硫基苯乙酸(Ⅳ)。

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16、

During the acetylation of ( 3-bromopropyl) benzene the products of the halogen exchange are observed, a reasonable explanation for the phenomenon is proposed and the disposal of the acetylation of ( 3-bromopropyl) benzene is studied at the same time.

对3-溴丙基苯的付克酰基化反应进行了研究,发现了卤素交换的现象,并对此做了合理的解释,同时对该反应的后处理进行了研究。

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17、

Racemic 2-methyl-1-phenylpropylamine was obtained by Friedel-Crafts reaction of benzene and isobutyryl chloride with the yield of 75.0%, then followed by Leuckart reaction in 85.0% yield.

本文以苯、异丁酰氯为原料通过傅克酰基化反应得到2-甲基-1-苯基丙酮,收率75.0%。

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18、

Toluene was reacted with isobutyryl chloride in the presence of aluminum chloride to give 2 methyl 1 ( 4 methylphenyl) propanone in 75% yield.

收率为92%~93%.在催化剂无水三氯化铝存在下,甲苯与异丁酰氯进行酰基化反应得2甲基1(4甲基苯基)丙酮,收率为75%。

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19、

The Friedel-Crafts acylation reactions of benzothiophene were carried out, and the effect of microwave radiation on the reaction was analyzed.

对苯并噻吩的傅-克酰基化反应进行了研究,并讨论了微波辐射对反应的影响。

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20、

The paper discussed two acidylating reaction of Norfloxacinum, and the feasibility of appling these two reactions to teaching experiments.

本文探讨了氟哌酸的两个酰基化反应,及其作为教学实验的可行性。

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