The key intermediate, Ethyl 4-( 4-ethoxy-4-oxobutyl) benzoate ( 6), was obtained from benzene via Friedel-Crafts acylation, Huang reduction, saponification followed by acidification and esterification in 36.6% yield.

1、

Up to now, the methods for preparing aromatic ketones still involve homogeneous metal chlorides or protonic acid used as catalysts in batch reactors via Friedel-Crafts acylation in industry.

目前，工业上通过Friedel-Crafts酰基化反应制备芳酮类化合物的工艺仍然是以均相的金属氯化物或质子酸等为催化剂，采用釜式反应器。

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2、

Friedel-Crafts acylation is one of the most important synthetic reactions for the preparation of aromatic ketones, which are widely used as intermediates in fine chemicals and pharmaceutical industries.

芳酮类化合物是重要的精细化工和医药中间体，Friedel-Crafts酰基化反应是合成芳酮类化合物的最重要的方法。

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3、

Method ( 2H)-2-cyclohexyl-3,4-dihydropyrrolo [ 1,2-a] pyrazin-1-one was synthesized from methyl pyrrole-2-carboxylate via substitution and cyclization, and the target compounds 6-aryl derivatives were obtained by Friedel-Crafts reaction.

方法以2-吡咯甲酸甲酯为原料，经取代、环合，制备（2H）-2-环己基-3,4-二氢吡咯[1,2-a]吡嗪-1-酮（3）；通过Friedel-Crafts酰基化反应，制得其6-酰基衍生物4a~4j。

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4、

Progress on Friedel-Crafts Acylation Reaction

Friedel-Crafts酰基化反应研究进展

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5、

An excess of olefin produces a negative effect on the reaction.

DMB过量对该酰基化反应产生负面影响。

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6、

The reaction conditions of Friedel-Crafts acetylation and Claisen condensation were investigated.

并研究了Friedel-Crafts酰基化反应和Claisen缩合反应的工艺条件。

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7、

Friedel-Crafts acetylation of salicylamide ( SA) with acetyl chloride to5-acetylsalicylamide using triethylammonium chloroaluminate ionic liquid ( IL) as both catalyst and solvent was investigated.

实验以盐酸三乙胺-三氯化铝离子液体（IL）为催化剂，催化水杨酰胺（SA）与乙酰氯进行傅克酰基化反应合成5乙酰水杨酰胺。

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8、

Application of Zeolite Molecular Sieves in Friedel-Crafts Acylation Reactions

沸石分子筛在Friedel-Crafts酰基化反应中的应用

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9、

Friedel-Crafts acylation is important and fundamental organic reactions for preparing aromatic ketones.

Friedel-Crafts酰基化反应是一类重要的基础有机反应，是合成芳香酮的主要反应。

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10、

A review of aluminium chloride based catalysts used in Friedel-Crafts acylation reactions

三氯化铝系列催化剂在Friedel-Crafts酰基化反应中的应用进展

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11、

Carboxylic crosslinked polystyrene ( PS-COOH) microsphere has been prepared by Friedel-Crafts acylation with phthalic anhydride.

选用邻苯二甲酸酐以傅克酰基化反应制备了聚苯乙烯（PS）羧基化弱酸性离子交换树脂。

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12、

The results show the camphene can be acylated in the presence of Lewis acid catalyst.

结果表明，在Lewis酸催化下莰烯可以进行C酰基化反应。

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13、

The Friedel-Crafts acylation is one of the most important approaches to synthesize aromatic ketones and has been widely used in the production of fine chemicals and pharmaceutical intermediates.

傅克酰基化反应是合成芳酮的重要途径，广泛应用于精细化学品和医药中间体的合成。

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14、

Study on Friedel-Crafts Acylation of Aromatic Compounds Catalyzed by Zeolite Molecule Sieves

沸石分子筛催化芳环化合物的Friedel-Crafts酰基化反应的研究

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15、

It was prepared from 4-aminobenzaldehyde and 3-( 4-formylphenylazo)-4,5-dihydroxynaphthalene-2,7-disulphonic acid by diazotization, coupling reaction, yield was 52.6%.

以自制的对甲酰基苯偶氮变色酸和4氨基安替吡啉为原料，经重氮化、偶合反应制备上述目标化合物，产率为52.6%。

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16、

Methods RLS spectra was used to determine trace nitrite by the diazotization-coupling reaction between sulfanilic amide-N, N-dimethyl aniline-nitrite.

方法利用磺胺-N，N-二甲基苯胺-亚硝酸根间发生的重氮化-偶联反应，通过共振散射光谱法测定痕量亚硝酸根。

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The reaction was proved to be an exothermic reaction by dynamic and thermodynamic which agrees with experimental results.

通过热力学及动力学计算，重氮化-席曼反应是剧烈的放热反应，与实验结果相吻合。

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18、

Research in Theory of Reoxidation and Coincidence Reaction

重氮化与偶合反应的理论研究

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Special reaction conditions of diazotization on of aromatic amines

芳香伯胺重氮化的特殊反应条件

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20、

Application and study on resonance scattering spectra of diazotization-coupling reaction

亚硝酸根重氮化-偶联反应共振散射光谱测定

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