The methylation of promoter region CpG islands is one of main ways for inactivating tumor suppressor gene, DNA repair gene and pro-apoptotic gene.

  • 启动子区CpG岛高甲基化(hypermethylation)是抑瘤基因、DNA修复基因、促凋亡基因失活的主要方式之一。
  • 来源:互联网摘选更新时间:2026-07-01 14:28:55

  • 重点词汇
  • theart.这个;指已提到或易领会到的人或事物;指独一无二的、正常的或不言而喻的人或事物;用以泛指;与形容词连用,指事物或统称的人;用于姓氏的复数形式前,指家庭或夫妇;(指特定用途的事物)足够,恰好;每,一;当前的,本,此;(重读,表示所指的为知名或重要的人或事物)
  • waysn.方法;(做某事现有的)方法和资源;你不可能做到两全其美;(所说的话)不止一个意思;路( way的名词复数 );方法;方向;某方面;
  • inactivatingv.使不活泼,阻止活动( inactivate的现在分词 );
  • forconj.因为,由于;
  • suppressorn.镇压者,抑制物,干扰抑制器;
  • andconj. 和;与;而且;于是;然后
  • methylation甲基化作用;
  • DNAabbr.脱氧核糖核酸(deoxyribonucleic acid);(美国)国防部核子局(Defense Nuclear Agency);
  • isvt.& vi. 是(be的三单形式);
  • 相关例句
1、

Objective: Study the expression of tumor suppressor gene, DNA repair gene and telomerase component in acute leukemia, discuss their effects on the occurrence and development of leukemia and their clinical meanings.

目的:研究抑癌基因、DNA修复基因及端粒酶在白血病细胞中的表达,探讨其对白血病发生、发展的作用和临床意义。

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2、

Repairing experimental femoral head necrosis of goat with BMP-2 gene medicine

BMP-2基因给药修复实验性羊股骨头坏死

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3、

DNA repair approach has focused on gene targeting or gene replacement whereby the defective gene is removed and a normal gene is inserted at the same position in the chromosome and so it maintains the corrected gene's expression in the natural context.

基因原位修复策略是一种直接的基因疗法,它针对基因缺陷部位进行修复,保持了基因原有的染色质环境,因此是一种理想的靶向性基因治疗方式。

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4、

Among them, a newly developing technology, called targeted gene repair mediated by oligonucleotides, is a better way for genetic disorders than traditional strategies.

近年来新兴的寡核苷酸介导的基因定点修复技术,就是其中一种比传统策略更具优越性的基因治疗方法。

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5、

The mechanism of cooperation maybe that caffeine inhibits gene repair of osteosarcoma cells, and reverses the drug resistance of osteosarcoma cells to taxol.

其协同机制可能是咖啡因抑制了骨肉瘤细胞某些基因的修复,并逆转了肿瘤细胞对于紫杉醇的耐药性。

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6、

Those novel genes can recover genome annotation, which is an effective complement of automate genome annotation system.

这些新基因可以修复基因组的注释,是对基因组自动注释系统的有效补充。

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7、

It is our genes that repair the damage caused by disease and restore us to health;

正是我们的基因,修复因疾病引起的损害,并使我们恢复健康;

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8、

Mechamism Studies of Targeted Gene Repair Mediated by Single-Stranded Oligonucleotides

单链寡核苷酸介导基因定点修复的作用机制研究

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9、

And is negative for CD34, CD45, CD14. Many investigators gain good results when they use MSCs as seed cells in bone tissue engineering to repair bone defect of animal model by autotransplantation or allotransplantation into immunodeficiency animals.

应用MSCs作为骨组织工程种子细胞的研究很多,在自体移植修复骨缺损动物模型和异基因移植修复免疫缺陷动物骨缺损模型实验中取得了良好的效果。

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10、

Aflatoxin ( AFT) was highly concerned in the study of environmental carcinogens. And the relationship between genetic polymorphisms and susceptibility to cancer attracted more attention too.

黄曲霉毒素(aflatoxin,AFT)是环境致癌物研究的热点之一,而抑癌基因、修复酶基因及代谢酶基因多态性与肿瘤易感性的关系也很受重视。

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11、
12、

The interaction between genes and environmental risk factors was analyzed by multivariate logistic regression model.

应用多因素Logistic回归分析,对在食管癌发生中代谢酶基因与修复酶基因的交互作用以及环境-环境、基因-环境的交互作用进行了分析。

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13、

With a little genetic tinkering, fast growing fish and freeze resistant fruits will help feed an overpopulated planet, but such hybrids could unwittingly wipe out the food chain.

有了稍经基因修复、快速养殖的鱼和防冻水果,人口过多的星球将获得足够的食物,不过,这些合成物可能不知不觉地彻底摧毁食物链。

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14、

Finally, we performed hematopoietic differentation on the patient-specific iPS cells and gene-corrected iPS cells both in vitro and in vivo.

最后将病人特异的干细胞系和基因修复的干细胞系分别进行体外定向造血分化,并建立了体内移植的小鼠模型。

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15、

These phenomena provide simple and easy method for generating definite mutation or gene rectification.

该现象为创造定点突变,基因修复提供了简便易行的方法。

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16、

Repair of radial bone defects of rabbits by adenovirus mediated human bone morphogenetic protein-2 gene

腺病毒介导的人骨形态发生蛋白2基因修复兔桡骨缺损

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17、

Direct bone morphogenetic protein 2 gene therapy for repairing segmental radial defect in rabbits

骨形成蛋白2基因修复兔桡骨缺损的实验研究

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18、

Effect of Maize Cell-free Extract on Genetic Repair Directed by Oligonucleotides

玉米细胞抽提物在寡核苷酸指导的基因修复中的作用

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19、

Screening of phospholipid hydroperoxide glutathione peroxidase genes in plants

植物谷胱甘肽磷脂氢过氧化物酶基因的筛查

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20、

Screening the sensitive deafness genes in newborn is imminent.

在新生儿中开展耳聋易感基因的筛查工作刻不容缓。

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