Structure and Function of Stable RNA Hairpins

With the development of molecular biology and structural biology, the interaction energy between organic molecules and biological macromolecules has been understood profoundly. The optimization model has been developed from lock and key-based rigid one to induced-fit-based flexible one.

随着分子生物学和结构生物学的发展，人们对生理活性分子与生物大分子的相互作用有了更加深刻的认识，从基于锁钥原理的全刚性模型逐渐发展成为基于诱导契合的柔性模型。

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With the development and application of the new technologies, such as molecular biology, structural biology and protein engineering, many progresses have been made in the research of structures and functions of xylanase.

随着分子生物学、结构生物学的发展及蛋白质工程的应用，对木聚糖酶结构和功能的研究不断深入。

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This paper briefly discusses the progress and prospect of structural biology study, and a brief review of the status of structural biology in life sciences and the main research methods is given.

本文简要介绍了结构生物学研究进展及发展。概括介绍了结构生物学在整个生命科学中的地位，结构生物学的研究内容和主要研究方法。

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With the development of structural biology, the number of compounds and proteins are increasing, virtual screening application are facing the dual challenges of mass data storage and large-scale computation.

随着结构生物学的发展，化合物数量和靶标蛋白数量都在不断增加，虚拟筛选应用将面临海量数据存储和大规模计算处理的双重挑战。

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With the development of structural biology, this family of proteases as a typical representative of the enzyme, many members of the structure has been successive resolved.

随着结构生物学的发展，此家族蛋白酶作为酶的典型代表，很多成员的结构都被人们所相继解析。

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Electron microscopy is an important tool in structural biology and can be used to elucidating the structures of macromolecular complexes and assemblies, subcellular organelles and cells.

电子显微学是结构生物学的重要分支，已经成为一种公认的研究生物大分子、超分子复合体及亚细胞结构的有力手段。

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We thought that there was a great opportunity for structural biology which could drive much of the biochemical and mechanistic studies.

因此我们就认为对结构生物学来说这也是一个伟大的机会，因为结构生物学往往可以推动很多生物化学及其机制的研究。

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In this thesis, the structure function relationships of 2 kinds of molecules from different biological resources were studied.

本课题遵循结构生物学的专业方向以晶体学的方法研究两种生物来源的化合物的结构与功能的关系。

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Global minimization methods and their applications to structural molecular biology have made significant progresses in recent years.

全局极小化方法及其在结构生物学中的应用近年来取得了显著的进展。

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Nowadays the in silico scenario for drug design is totally dependent on structural biology and structural bioinformatics.

现在，药物设计的计算机方案完全依赖于结构生物学和结构生物信息学。

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Structural Biology research field.

结构生物学研究领域。

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An outline of Energy Structure Biology

能量结构生物学初探

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Advances in this field is a new direction of structural biology for this century.

这一领域代表着本世纪结构生物学的一个新方向。

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The advance on research technology of structural biology

结构生物学研究技术的进展

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The structural biological meaning and possible applications of the finding were discussed.

讨论了该结果的结构生物学意义及其在基因工程领域可能的应用。

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Advances of electron microscopy and its applications in structural biology

电子显微学在结构生物学研究中的新进展

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The construction of receptor structure based on the molecular biology and structural biology of α_1-AR and rational design on α_1-AR antagonists are introduced. And the further application of this method is also prospected.

介绍了基于α1-AR受体分子生物学与结构生物学的受体结构构建及其拮抗剂的设计，并对该技术的发展进行了展望。

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Expression and Purification of eIF-5A for Structural Biology Study

结构生物学研究中的eIF-5A的表达与纯化

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An article entitled Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II was published in the July 1st, 2005 issue of the journal Cell. This research work was accomplished by the Tsinghua-Institute of Biophysics Joint Research Group for Structural Biology.

由清华大学-中科院生物物理所结构生物学联合研究小组完成的线粒体呼吸链膜蛋白复合物II的晶体结构研究成果以Article的方式发表在2005年7月1日出版的Cell上。

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Synchrotron radiation X-ray diffraction facility at NSRL and its applications in macromolecular crystallography

同步辐射X射线衍射装置及其在结构生物学中的应用

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