The advance on research technology of structural biology

The structural biological meaning and possible applications of the finding were discussed.

讨论了该结果的结构生物学意义及其在基因工程领域可能的应用。

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Advances of electron microscopy and its applications in structural biology

电子显微学在结构生物学研究中的新进展

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The construction of receptor structure based on the molecular biology and structural biology of α_1-AR and rational design on α_1-AR antagonists are introduced. And the further application of this method is also prospected.

介绍了基于α1-AR受体分子生物学与结构生物学的受体结构构建及其拮抗剂的设计，并对该技术的发展进行了展望。

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Expression and Purification of eIF-5A for Structural Biology Study

结构生物学研究中的eIF-5A的表达与纯化

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An article entitled Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex II was published in the July 1st, 2005 issue of the journal Cell. This research work was accomplished by the Tsinghua-Institute of Biophysics Joint Research Group for Structural Biology.

由清华大学-中科院生物物理所结构生物学联合研究小组完成的线粒体呼吸链膜蛋白复合物II的晶体结构研究成果以Article的方式发表在2005年7月1日出版的Cell上。

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Synchrotron radiation X-ray diffraction facility at NSRL and its applications in macromolecular crystallography

同步辐射X射线衍射装置及其在结构生物学中的应用

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Computer aid drug design ( CADD) is a rapid developing frontier branches of science involving Chemistry, Biology, Computer Science, Informatics, Mathematics and Physics.

计算机辅助药物设计（CADD）涉及化学、生物学、计算机科学、信息学、数学和物理学等领域，是一门新兴的、快速发展的边缘学科。

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In the search for biomaterials we have identified ovine forestomach matrix ( OFM), a thick, large format ECM which is biochemically diverse and biologically functional.

在探索生物材料过程中，我们鉴定出具有多种生物化学和生物学功能的羊贲门窦基质（OFM），一种大而厚的细胞外基质。

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First the ESR technology was applied to physics, chemistry and biology and other areas.

ESR方法首先应用于物理学、化学、生物学等领域。

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Triplex DNA tools on this basis are of great interest from the standpoint of chemistry, medicine and biology.

以反基因战略为背景的各种三链DNA工具无论从化学、生物学和药物学的角度都具有重大的理论及现实意义，已经成为近几年来的研究热点之一。

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Michael reaction acceptors ( MRAs) are the biologically active molecules which contain electrophilic moieties, which directly or indirectly involved in the life processes, they are also regulators in many signaling pathways in cells, and play an important role in chemical biology studies.

迈克尔反应受体分子为一类含有亲电共轭体系官能团的生理活性分子，它们直接或间接参与许多生命过程，同时也是细胞中许多信号转导途径的调节者，在化学生物学研究中起着重要作用。

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In order to meet the development of this new discipline, many universities have established the related laboratory or research group with the chemical biology discipline, and started to recruit the undergraduate or graduate students ( master or doctor) of chemical biology speciality.

为了顺应这一新学科发展的需要，众多高校纷纷建立与化学生物学学科相关的实验室或研究组，并开始招收化学生物学专业的本科生和研究生。

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In contrast to TOS, diversity-oriented organic synthesis ( DOS), aiming for creation of molecular structural diversity, is emerging as a frontier research direction in recent years. It closely associates with research in chemical biology or chemical genetics.

与之相对应，多样性导向合成是以产生分子结构多样性为目的，是近年发展起来的一个前沿研究方向，与化学生物学或化学基因组学的研究有密切的关系。

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But the contents of elementary knowledge about the chemical biology are still not very clear, and the emphasis points of the chemists, biologists and pharmacists about the contents of chemical biology are various from the view of different discipline.

但是，有关化学生物学的基本知识结构仍然不清楚，化学、生物学和药学家对于化学生物学内容的理解均本着本学科相关的一些方面，侧重点各不相同。

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As a new interdiscipline between chemistry and life science, chemical biology has springing up in the world and becoming a major direction in the further ten year or much more time.

综述了化学生物学作为一个化学与生命科学交叉的新兴学科，正在世界各国迅速兴起，并逐渐成长为未来几十年或更长一段时间内的重要前沿方向。

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Chemical biology and diversity-oriented organic synthesis make possible the systematic exploration of biology and artificial transcription factors be used as a probe for the discovery of new insights into life processes.

化学生物学和结构多样性有机合成使系统研究生物学成为可能，人工转录因子可以用作探针来发现生命过程中新的奥秘。

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Researchers have already claimed that the report, which is published in the journal Nature Chemical biology, could lead to new ways to prevent and treat flu.

研究人员们称，这项研究成果能为防治流感提供新办法。研究报告将在《自然化学生物学》期刊上发表。

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An example of the role of chemical biology in the development of the bio| chip technology is given to illustrate the basic features of current chemical biology.

本文以化学生物学在生物芯片技术发展中扮演的角色为例讨论当前化学生物学发展的特点。

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The study was supported by the National Institutes of Health, The Skaggs Institute for Chemical Biology, and the Canadian Institutes of Health Research.

该研究由国立卫生研究院，斯卡格化学生物学研究所和加拿大卫生研究院资助。

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How the protein molecules to utilize the heme to perform different biological function, is always the research focus in chemical biology and protein chemistry.

相同的血红素辅基如何被不同的蛋白质分子所利用，来执行不同的生物功能，一直是化学生物学和蛋白质化学研究领域所关注的重点。

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