Methods To make a statistic analysis of the Oral Hypoglycemic agents used in my hospital during the period 2000~ 2003 with the sum of money, DDDs and daily cost.

An experimental diabetic model was induced by vein injection of alloxan monohydrate ( 100 mg/ kg). We observed the effects of LBP-D, hypoglycemic agents alone or in combination, on blood glucose and the functions of cellular immunity in alloxan-induced diabetes mice.

利用四氧嘧啶静脉注射（100mg/kg）诱导的糖尿病小鼠模型，观察LBP-D单独及与降糖药联合应用对小鼠血糖和细胞免疫功能的影响。

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Dipeptidyl peptidase ⅳ inhibitor ( dipeptidyl peptidase-4 inhibitor, DPP-ⅳ inhibitors) is currently developing a new, efficient one of hypoglycemic agents.

二肽基肽酶Ⅳ抑制剂（？）（dipeptidyl peptidase-4inhibitor，DPP-Ⅳ抑制剂）就是目前开发的一种新的、有效的降糖药之一。

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The results provided theoretic basis for the molecular biochemical mechanism of POV lowering hyperglycemia, and provided experimental base for exploring a new lowering hyperglycemia drug.

此结果为POV降低高血糖的分子生化机理提供理论依据，亦为探讨治疗糖尿病新的降糖药提供实验基础。

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Conclusions The effect of treating hyperglycemia on insulin pump therapy in newly diagnosed T2DM is better than that in T2DM with failure to oral antidiabetic therapy.

结论初诊的T2DM患者可能较口服降糖药效果差的T2DM患者对胰岛素泵降糖效果更满意。

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Methods Forty type 2 diabetes patients which could not control the blood glucose successfully with drugs were divided into two groups randomly: glargine group ( 20 cases) and mixed insulin group ( 20 cases).

方法40例用口服降糖药血糖控制不良的2型糖尿病患者随机分为甘精胰岛素组（简称甘精组）和预混胰岛素组（诺和灵30R，简称预混组），每组各20例。

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This is true of many other diabetes pills, too.

其他许多降糖药也有类似情况。

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Thirty-four NIDDM patients were given 4-month dietary control and/ or oral hypoglycemic agent treatment and it showed that the GFR, kidney volume and UAE were partially reduced in 12 patients with improved metabolic control;

34例NIDDM患者经饮食控制和／或口服降糖药治疗4个月后进行了复查，结果显示：12例代谢改善者的GFR、肾脏体积和UAE有不同程度的恢复；

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Cost-effectiveness analysis of drugs in treatment of type 2 diabetes mellitus

2型糖尿病患者口服降糖药的成本效果分析

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⑵ With the increase of course, inpatients respectively with therapy of OHA or insulin significantly decreased and increased, but the overall ratio of insulin was low.

⑵老年DM住院患者随病程延长口服降糖药治疗者明显减少，胰岛素应用比例逐渐增加，但总体胰岛素使用率较低；

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The Retrospectively Dynamic Analysis of Hypoglycemic Agents in 2006-2008 at Our Hospital

我院2006&2008年降糖药回顾性动态分析

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[ Methods] Included were 31 cases of elderly diabetes mellitus diagnosed by criteria of WHO. All patients had lower effect on oral hypoglycemia agent, were added to given Novolin N injection at bedtime.

方法31例符合WHO诊断标准口服降糖药治疗血糖控制不满意的老年糖尿病患者，联合睡前注射诺和灵N。

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The two antihypertensive drugs are characteristics of specific receptor, medication safety, well-tolerated, significant antihypertensive effect, lower side effect.5-carboxylic acid Losartan ( EXP-3174) is the active metabolite of Losartan.

这两种降糖药具有受体作用的专一性，用药安全，耐受性良好，抗高血压作用显著，副作用小的特点。5-羧酸洛沙坦（EXP-3174）是洛沙坦的活性代谢产物。

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Conclusion Bedtime basal insulin added to oral therapy can safely achieve HbAlc less than 7% in majority of patients with type 2 diabetes with HbAlc> 7.5% on oral agents alone.

结论口服降糖药治疗且血糖控制不良的2型糖尿病患者，睡前加用基础胰岛素，可使绝大多数患者血糖获得理想控制（HbAlc≤7%）。

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[ Conclusion] Recombinant human insulin injection Novolin N and oral hypoglycemia agent combination therapy on elderly diabetes mellitus is safety and effective.

结论用重组人胰岛素诺和灵N联合口服降糖药治疗老年糖尿病是安全有效的。

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Sodium-glucose co-transporter is currently developing a new, efficient one of hypoglycemic agents.

钠-葡萄糖共转运体抑制剂（sodium-glucose co-transporter，SGLT-2抑制剂）是目前开发的一种新的、有效的降糖药方向之一。

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Methods 80 cases were randomly divided into acupuncture treatment group ( A), exercise therapy group ( B), acupuncture plus exercise therapy group ( C), and control group ( D) treated with rational diet and oral administration of hypoglycemia agents.

方法：80例患者随机分为针刺治疗组（A）、运动疗法组（B）、针刺结合运动疗法组（C）、和单纯进行合理饮食及口服降糖药治疗对照组（D）。

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Clinical observation of recombinant human insulin injection novolin N and oral hypoglycemia agent combination therapy on elderly diabetes mellitus

诺和灵N联合口服降糖药治疗老年糖尿病的临床观察

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Result: The DDDs of oral antidiabetic agents rised gradually from 2001 to 2003.The front of DDDs were among Gliclazide, Tolbutamide and Metformin.

结果：2001～2003年我院口服降糖药的DDDs呈现逐年上升，其中格列齐特、甲苯磺丁脲、二甲双胍位居前列；

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Survey the actuality of using oral hypoglycemic drug in our hospital

我院口服降糖药使用现状调查与分析

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The safety indicators, liver and kidney function, ECG, blood, urine, stool routine examination, with no abnormal changes, and no complication occurred. Conclusions: 1.

两组患者安全性指标肝肾功能、心电图、血、尿、大便常规检查均无异常变化，无并发症发生。

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