convulsive seizure

Objective To explore the effects of propofol and thiopental sodium injection on convulsive seizure in electro-convulsive therapy ( ECT) and to provide evidence to help the selection of intravenous anaesthetics in improved ECT.

目的探讨丙泊酚与硫喷妥钠对电抽搐治疗时抽搐发作影响特点的差异性，为改良式电抽搐疗法中静脉用麻醉药物的选择提供依据。

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Clinical and Electroencephalogram Analysis of Cases with Convulsive Seizure as First Symptom

以抽搐样发作为首发症状的临床与脑电图分析

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Electroconvulsive, or electroshock, therapy involves passing an electric current through the patient's head between two electrodes placed over the temples and thus causing a convulsive seizure;

电击疗法是在双颞部各放置一块电极板，通以交流电，使意识立即丧失并引起抽搐发作。

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Clinical features include bilateral pigmentary degeneration of the retina, optic atrophy and progressive dementia, and lay in bed after several years with convulsive seizure, opisthotonus, limb rigidity, hyperreflexia, pyramidal sign positive;

主要表现为视网膜色素变性、视神经萎缩、进行性痴呆，数年后完全卧床，伴有抽搐发作，角弓反张、肢体强直、反射亢进，和双侧病理征阳性；

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Conclusion Thiopental sodium can increase the excitation threshold of brain cortical neurons and decrease the level of convulsive seizure induced by ECT.

结论硫喷妥钠可上调大脑皮质神经元的兴奋阈值，降低电抽搐治疗时的痉挛发作程度。

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Propofol may decrease the excitation threshold, and increase the level of convulsive seizure under the same ECT parameters, but may have the potential to induce epileptic seizure.

丙泊酚可能会使兴奋阈值下调，相同治疗参数引起的痉挛发作较好，但丙泊酚有诱发癫痫样发作的可能。

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