antimitotic

Establish a mathematical model of K562 cells growth and treatment with the antimitotic agent docetaxel in vitro.

同时，以K562为对象，建立了多烯紫杉醇诱导K562细胞凋亡的数学模型。

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As a kind of antimitotic drugs, Vinca alkaloids can inhibit microtubule assembly and induce tubulin self-association into coiled spiral aggregates.

长春花生物碱作为一类抗有丝分裂药物，能够抑制微管聚合并诱导聚合的微管蛋白解聚。

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Taxol, extracted from the bark of American pacific yew tree, is an antimitotic agent. It can promote the stabilization of the microtubule and inhibit mitosis and thereby can effectively accelerate apoptosis and control contraction 、 proliferation 、 migration.

紫杉醇是最早从美国西部紫杉中分离得到的一种有独特抗癌活性的天然药物，通过稳定微管、抑制有丝分裂，从而有效的控制细胞的收缩、增殖和移行、促进细胞凋亡。

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Objective conidia of Pyricularia Oryzae to the screening of antimitotic constituents from marine animal sea hare.

目的:利用稻瘟霉生物活性成分跟踪筛选模型,筛选海兔中抗有丝分裂活性成分.

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This procedure using antimitotic medium combining with serum free medium could eliminate fibroblasts effectively, injure less Schwann cells, and yield up to 98% purified Schwann cells.

这种抗有丝分裂法结合无血清培养法，既能有效去除成纤维细胞，又能减少对SC的损伤，获得的SC纯净度可达98%。

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Study on the relationships between the electronic structure and antimitotic activity of paclitaxel analogues(ⅰ)

紫杉醇类似物的电子结构与抗癌活性关系的研究（Ⅰ）

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Objective: To apply conidia of Pyricularia Oryzae to the screening of antimitotic constituents from marine animal sea hare.

目的：利用稻瘟霉生物活性成分跟踪筛选模型，筛选海兔中抗有丝分裂活性成分。

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Conclusion: The proportions of strains with antimicrobial activities and antimitotic activities are both above 20%, suggesting that the East China Sea has rich resources of medicinal microorganisms.

结论：分离得到的抗菌活性菌株，抗稻瘟霉分生孢子活性菌株的比例均达到20.0%以上，说明东海具有丰富的药用微生物资源。

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