GSK

ConclusionNE-induced rat cardiac remodeling decreased the GSK-3� � protein and increased in DVL-1 protein in cardiofibroblasts.

结论NE致 大鼠心肌重塑过程中GSK -3 β蛋白表达显著降低,DVL-1蛋白表达显著升高,可能与心肌纤维化有关.

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Communication and coordination with GSK quality leadership team, quality audit team and AP quality team.

与相应GSK质量管理团队 、 质量审计团队,亚太区质量团队沟通协调.

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GSK is one of several multinational groups to have built R& D centres in China, aiming to tap the strengthening science base and tailor drugs for the growing local market-already the world's second-largest after the US.

GSK是在中国设立研发中心的数家跨国制药企业之一，旨在利用中国日益增强的科研基础，并针对中国市场研发药物——不断增长的中国市场，已经是仅次于美国的全球第二大医药市场。

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GSK's vaccine development won't be part of the new company, according to Bloomberg News.

彭博新闻社消息称,葛兰素史克的疫苗开发部将不会差与新公司的组建.

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The US Department of Justice legal filings said GSK made use of "cash payments disguised as consulting fees, expensive meals, weekend boondoggles and lavish entertainment".

美国司法部（us department of justice）提交的法庭文件称，葛兰素史克“将现金贿赂伪装成咨询费、高价餐费、周末休闲活动开支和奢侈娱乐活动开支”。

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The unusual arrangement will give London-based GSK 85 percent equity and New York's Pfizer the remainder.

这项非同寻常的协议规定,总部在伦敦的葛兰素史克占了其中85%的股份,而剩下的归纽约的辉瑞所有.

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The drug company GlaxoSmithKline ( GSK) has announced plans for radical changes in the way it approaches neglected tropical diseases, a move that has caused intense debate.

制药公司葛兰素史克（GSK）宣布了在解决被忽视的热带病问题上的重大变革的计划，这一举动已经导致了激烈的辩论。

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Assuming GSK and Shenzhen can negotiate other obstacles, such as the need to placate Chinese regulators and maintain quality control, a successful partnership should boost sales of flu jabs while opening the door to further co-operation on more profitable vaccines.

如果gsk与深圳海王能够解决其它难题，例如令中国监管机构满意和保证质量控制，成功的合作关系则将会促进流感防疫针的销售，同时为在利润更丰厚的疫苗领域展开进一步合作打开大门。

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A decade ago Britain's GlaxoSmithKline ( GSK) got a bloody nose in South Africa when it tried too vigorously to defend patents on an HIV drug.

十年前，英国的制药公司葛兰素史克在南非试图保护一种抗艾滋病药物的专利，因过于积极而碰得头破血流。

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Like BP, another FTSE 100 company under attack, GSK is finding the political climate hard and capricious.

与另一家饱受攻击的富时100成份股公司&英国石油（BP）一样，葛兰素史克也体会到了政治环境是如此的严酷和变幻莫测。

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GSK, with its checkered history of corruption scandals, seems to deserve little sympathy.

之前，葛兰素史克已经有过几次行贿史了，所以似乎不值得同情。

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Among the institutional grants was a GlaxoSmithKline Institute for Digestie Health Research award.

公共机构奖励的是葛兰素史克公司(GSK)的消化健康研究奖.

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The latest GSK agreement does not involve any cash payment or equity stake.

GSK签署的最新协议不涉及现金支付或股权。

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MAPK inhibitor ( PD 98059 ) inhibited the phosphorylation of GSK-3 P and almost completely blocked oxLDL-induced tubular EMT.

MAPK抑制剂 PD98059 可抑制GSK -3 β的磷酸活化,并几乎完全阻断oxLDL诱导的肾小管上皮细胞转分化,但对LDL诱导 的小管上皮细胞转分化只有部分阻断作用.

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GSK have added that all tested influenza virus subtypes have shown no resistance to zanamivir and that they have sufficient supplies for the2008-2009 flu season.

葛兰素史克（GSK）补充说，所有的受试流感病毒的亚型对扎那米韦没有耐药性，并且他们可以在2008-2009年感冒流行季节保证充足的供应。美国报告的流感毒株耐奥斯他韦（达菲）

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MAPK inhibitor ( PD98059) inhibited the phosphorylation of GSK-3P and almost completely blocked oxLDL-induced tubular EMT.

MAPK抑制剂PD98059可抑制GSK-3β的磷酸活化，并几乎完全阻断oxLDL诱导的肾小管上皮细胞转分化，但对LDL诱导的小管上皮细胞转分化只有部分阻断作用。

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GSK hopes to induce a stronger immune response by combining RTS, S with a vaccine from Crucell, another drug firm.

葛兰素史克公司希望使用RTS，S和另一家制药公司Crucell的一种疫苗的结合体来引起更强烈的免疫反应。

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But the Serious Fraud Office has since opened its own criminal investigation and Downing Street on Tuesday adopted a nuanced stance: GSK is a strong British company.

但英国的严重欺诈办公室（SFO）最近展开了自己的刑事调查，唐宁街周二在这件事上采取了微妙的姿态。一位发言人说：葛兰素史克是一家实力强大的英国公司。

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The GSK project does not try to provide the medical care that migrant workers and their families are lacking. Rather, it tries to prevent them getting sick, by offering basic preventive education on topics such as sanitation, childhood nutrition and childhood diseases.

新市民健康关爱计划的宗旨不是向农民工及其亲属提供他们缺乏的医疗服务，而是试图通过涉及卫生、小儿营养和儿科疾病等问题的基本预防性教育，来预防他们生病。

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We should not feel too sorry for GSK – the Avandia affair is far less costly to it than the Gulf of Mexico spill to BP, and its operating margin remains at about 30 per cent.

我们不应过于同情葛兰素史克&文迪雅事件带给它的损失，要远远小于墨西哥湾漏油事件带给BP的损失，且该公司的营运利润率仍保持在30%左右。

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By promoting drugs beyond the uses approved by the US Food and Drug Administration, GSK generated substantial short-term sales but lay the foundations for a series of regulatory actions.

通过鼓励患者将药品用于美国食品药品监督管理局（US Food and Drug Administration）批准范围之外的用途，葛兰素史克取得了可观的短期销售业绩，但也为监管机构的一系列整治行动埋下了种子。

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ObjectiveTo observe the expression of GSK-3� � and DVL-1 protein cardiofibroblasts in cardiac remodeling in rats.

目的观察大鼠心肌重塑过程中心肌成纤维细胞DVL-1蛋白及糖原合酶激酶 -3 β(GSK -3 β)蛋白表达变化.

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Mr Witty, however , has already announced big changes at GSK.

Witty先生也已经宣布要对葛兰素史克动大手术.

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Mr Humphrey, a veteran corporate detective based in China, was recruited by GSK in April 2013 to investigate a former employee suspected of running a smear campaign against it.

常驻中国的资深企业侦探韩飞龙，是在2013年4月受聘于GSK的，任务是调查一名被怀疑对该公司掀起一场诽谤运动的前雇员。

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After a whistleblower made allegations against the company last year, GSK first relied on an internal probe with external legal and auditor support.

在去年举报者提出指控之后，GSK最初依赖于内部调查，辅之以外部法律和审计支持。

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The gesture remains largely symbolic for GSK, however.

但对葛兰素史克来说, 这一姿态基本上仍只有象征意义.

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The latest wave of anti-trust investigations in China – first Qualcomm and now Microsoft and the ongoing criminal investigations involving GSK – is having an unsettling effect on global supply chains across a variety of industry sectors.

先是高通（Qualcomm），现在又是微软（Microsoft），还有正在接受刑事调查的葛兰素史克（GSK），中国的新一轮反垄断调查正对跨多种行业的全球供应链造成令人不安的影响。

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The French government has bought 94 million doses of "swine flu" vaccine from Baxter, GSK, Novartis and Sanofi to carry out the forced vaccination programme.

法国政府已经从巴克斯特公司、葛兰素史克公司、诺华公司和赛诺菲公荀购买了9400万剂疫苗进行强制免疫计划。

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Notably, treating mice with GSK-3 inhibitor showed a decrease in LPS-induced renal cell apoptosis in vivo.

除了抗发炎作用, GSK -3 抑制剂可以降低体内LPS诱发小鼠肾脏组织中的细胞凋亡现象.

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WPP, for example, first held a board meeting in China more than 20 years ago, while GSK held a board meeting in India last year.

比如说wpp二十多年前就第一次在中国举办了董事会会议，葛兰素史克去年也在印度召开了一次董事会会议。

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