DRN

Study of the Interaction of DNA with Anticancer-drug DRN

DNA与抗癌药物道诺霉素相互作用的研究

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Aim: To investigate the roles of serotonergic neurons in dorsal raphe nuclei ( DRN) in sleep.

目的：研究中缝背核（DRN）5羟色胺（5HT）能神经元在睡眠中的调节作用。

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Results It was found that a subpopulation of dorsal raphe nucleus ( DRN) neurons the intensely labeled with CTB. These CTB-labeled neurons were densely distributed in the dorsomedian part of the DRN with some in a surrounding area outside the DRN.

结果大部分DRN神经元有CTB的强阳性标记，且集中分布在DRN的背中线部分，部分分布在DRN外侧的周边区域。

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According to the distributing characteristic of highway pivotal infrastructure, including super large highway bridge and long-span and extra-long highway tunnel etc, aimed at the traffic safety management, the concept of Dumbbell Road Network ( DRN) is provided, and its boundary algorithm is especially discussed.

针对公路重大交通基础设施（如特大桥、长大隧道等）的分布特征，从交通安全管理的角度，提出哑铃型路网的概念，重点对其路网边界算法进行探讨。

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Results: Stimulation of DRN caused a significant decrease in rCBF by 44.29% ( P < 0.01) and reduced the vessel diameter and blood flow velocity of the small pial arterioles.

结果：电刺激DRN后脑皮质rCBF减少44.2%（P<0.01），软脑膜微动脉管径缩小，血流速度减慢，而尼莫地平可取消其作用。

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