telopeptide

Objective: To evaluate the efficacy of carboxyterminal cross_linked telopeptide of type I collogen ( ICTP) in the diagnosis of early bone metastasis from lung cancer.

目的：评价I型胶原羧基端吡啶并啉交联肽（Carboxyterminalcross linkedtelopeptideoftyplcollagenICTP）诊断肺癌早期骨转移的效能。

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Swimming could promote the biochemical markers such as serum osteocalcin, type B serum alkaline phosphatase and carboxyterminal propeptide of type ⅰ precollagen, and reduce type ⅰ collagen cross-linked N telopeptide.

游泳运动可以使血清骨钙素、B型血清碱性磷酸酶和Ⅰ型前胶原羧基端前肽等骨形成生化标志物显著升高，而骨吸收生化标志物I型胶原交联N末端肽显著下降。

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Relationship between rheumatoid arthritis and pyridinoline cross-linked carboxy-terminal telopeptide of type ⅰ collagen

类风湿性关节炎与Ⅰ型胶原吡啶交联终肽的关系

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Then their serum malondialdehyde ( MDA), superoxide dismutase ( SOD) and type I collagen telopeptide ( ICTP) were detected; the SPSS 10.0 software was used for linear regression and related analysis, and the correlation of MDA and SOD with ICTP was analyzed.

检测各组血清丙二醛、超氧化物歧化酶及I型胶原羧基端肽水平，用SPSS10.0软件进行直线回归及相关分析，分析各指标间的相关性。

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As a biomacromolecules, collagen has a rich source in various of tissues which can be separated and purified from these tissues. Removing the telopeptide with antigenicity, collagen can be processed to prepare biomaterials with excellent biocompatibility.

胶原作为来源丰富的生物大分子，可以从许多机体组织中进行分离提纯，去除端肽后的胶原可以消除其抗原性，并可用于加工制备成具有良好生物相容性的生物材料。

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The results showed that pepsin-solubilized collagens ( PSC) without telopeptide could be prepared at low temperature.

结果表明，低温提取可得到胃蛋白酶促溶且去除端肽的酸溶性胶原蛋白（PSC）。

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