protamine sulfate

object: to study the test for bacterial endotoxins in protamine sulfate injection and provide reference for its quality control.

目的：对硫酸鱼精蛋白注射液进行细菌内毒素检查的可行性研究，为该药品质量标准中制定内毒素检查项提供参考。

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protamine sulfate injection separation of myoglobin from tilapia by ammonium sulfate salting-out

鱼精蛋白硫酸盐注射液硫酸铵盐析法分离罗非鱼肌红蛋白的研究

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the results demonstrated that protamine sulfate had positive effect on the expression of antibodies about 3-4 times, compared with the study in vitro, the difference between emulsion and liposome had been greatly decreased.

结果显示加入鱼精蛋白后抗体表达水平提高约3-4倍，与体外实验相比乳剂与脂质体组的表达差距明显减小。

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results: diluted by bet-water for 240 times of protamine sulfate injection ( 10 mg/ ml), the injection showed no signs of interfering factors for its test for bacterial endotoxins.

结果：硫酸鱼精蛋白注射液（10mg/ml）在稀释240倍时无干扰作用，可用细菌内毒素检查法进行检查。

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residue detection of protamine sulfate from purified vero-cell rabies vaccines used for human

人用纯化Vero细胞狂犬病疫苗中硫酸鱼精蛋白残留量的测定

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objectives: to set up the bacterial endotoxins determination method for protamine sulfate injection.

目的：建立硫酸鱼精蛋白注射液细菌内毒素的检查方法。

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the results showed that the fluorescent intensity of cdte qds decreased when the concentration of protamine sulfate increased.

结果表明随着硫酸鱼精蛋白浓度的增大，量子点荧光强度逐渐降低。

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conclusion: test for bacterial endotoxins of protamine sulfate injection may be conducted for its quality control.

结论：硫酸鱼精蛋白注射液细菌内毒素检查是可行的。

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in conclusion, complexes were formed between dotap/ dope cationic lipid carriers and dna through electrostatic force, ternary complexes were obtained after adding protamine sulfate. four kinds of complexes could delivery dna vaccine in vitro and in vivo.

综上所述，DOTAP/DOPE阳离子脂质体、阳离子脂质乳剂与DNA通过静电作用自组装形成复合物，分别加入鱼精蛋白后得到三元复合物，这4种复合物均能介导基因的体外转染和体内表达。

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