1、

Background and Aim: Carcinoma is a type of multi-gene disease, and a complex process involved multi-factor, multi-stage and multi-gene mutation, which caused by activation of telomerase and cancer gene, devitalization of suppressor gene.

背景和目的:研究表明,肿瘤是一类多基因疾病,是由于端粒酶激活、癌基因激活或抑癌基因失活等引发的多因素、多阶段及多基因变异的综合病变过程。

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2、

Lats gene ( large tumor suppressor gene), first identified in Drosophila melanogaster, has its homologues in mouse and human.

lats基因(largetumorsuppressorgene)最早在果蝇中发现,在小鼠和人中均有同源基因。

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3、

Neurofibromatosis type 1 ( NF1) is a common, autosomal-dominant disorder caused by mutations in the NF1 tumor suppressor gene.

神经纤维瘤病(NF1)是常见的常染色体显性遗传性疾病,国外报道,其发病率高达1:3000。这种疾病是由于NF1基因的突变而发生的。

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4、

Expression of Tumor Suppressor Gene PTEN in Oral Squamous Cell Cancer Using Tissue Microarray Techniques

应用自制组织芯片研究抑癌基因PTEN在口腔鳞癌中的表达

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5、

Objective To study the potential value of RECK, a transformation suppressor gene, as a prognostic molecular marker for glioma.

目的探讨肿瘤抑制基因RECK作为胶质瘤预后指标的潜在价值,及相关金属蛋白酶MMP-9、MMP-2在胶质瘤中的变化与RECK的相互关系。

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Conclusion: RECK gene is supposed to be a tumor suppressor gene which may act by inhibiting the activity of MMPs.

结论:RECK基因在前列腺癌中的表达量明显下降,而MMP-2、MMP-9的表达量明显升高,RECK基因可能通过抑制MMP-2、MMP-9的表达起到抑癌基因的作用。

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7、

FHIT gene may be a hopful tumor suppressor gene in human squamous carcinoma of larynx.

初步说明FHIT基因可能是一种有潜势的抑癌基因。

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8、

Fragile histidine triad gene ( FHIT) is considered a tumor suppressor gene which was found in recent years.

脆性组氨酸三联体(fragile histidine triad,FHIT)基因是近年发现的一种抑癌基因。

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9、

The effect of UV light radiation on tumor suppressor gene p53 expression

紫外线照射对P53基因表达的影响

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10、

The study of molecular pathogenesis in medulloblastoma: Single-strand conformation polymorphism analysis of PTEN tumor suppressor gene

髓母细胞瘤分子病理学研究:PTEN抑癌基因单链构型多态性分析

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11、

Objective: Study the expression of tumor suppressor gene, DNA repair gene and telomerase component in acute leukemia, discuss their effects on the occurrence and development of leukemia and their clinical meanings.

目的:研究抑癌基因、DNA修复基因及端粒酶在白血病细胞中的表达,探讨其对白血病发生、发展的作用和临床意义。

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12、

The methylation of promoter region CpG islands is one of main ways for inactivating tumor suppressor gene, DNA repair gene and pro-apoptotic gene.

启动子区CpG岛高甲基化(hypermethylation)是抑瘤基因、DNA修复基因、促凋亡基因失活的主要方式之一。

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13、

Epigenetic Regulation of Tumor Suppressor Gene PTEN and Its Anticancer Mechanisms

肿瘤抑制基因PTEN的表观遗传调控及其抗肿瘤机制研究

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14、

E-cadherin can suppress tumor cell invasion and metastasis, and is considered as an invasion/ metastasis suppressor gene.

E-cadherin能抑制肿瘤细胞的浸润和转移,被公认为是浸润、转移抑制基因。

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15、

Analytical and technical consideration of P53 tumor suppressor gene mutation

P53肿瘤抑制基因突变分析的技术方法探讨

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16、

Detection of p53 Tumor Suppressor Gene Mutation in Nine Kinds of Malignant Lymphoma Cell Lines Using PCR-SSCP Technique

银染PCR-SSCP方法检测人9种恶性淋巴瘤细胞系p53抑癌基因的突变

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17、

A study of correlation between of occurrence of Wilms' tumor with p53 tumor suppressor gene mutation

小儿肾母细胞瘤的发生与p53抑癌基因突变关系的研究

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18、

Objective: To study P53 suppressor gene mutation of pancreatic neoplasm in the Inner Mongolia Autonomous Region.

目的:了解内蒙古地区胰腺癌患者P53抑癌基因的突变情况。

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19、

P53 tumor suppressor gene mutation and protein accumulation in multifocal esophageal precancerous lesions among high risk population in Henan

食管癌高发区人群多灶性食管癌前病变的P53肿瘤抑制基因变化研究

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20、

Expression of the tumor suppressor gene P~ ( 16) in arsenic keratosis by hybridization in situ

原位杂交检测砷角化病表皮P~(16)基因的表达

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