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Conclusion: RGD peptide as an Alpha ( v) integrin antagonist has not only targeted drug delivering function but also direct tumor-killing effects. RGD peptide is an ideal therapeutic agent for potential tumor targeting therapy.

结论:RGD肽作为αv整联蛋白的一种拮抗剂,不仅具有药物、基因治疗载体的导向运输功能,更具有肿瘤的直接杀伤效应,是一种理想的肿瘤靶向性治疗药物。

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Experimental study of nerve allograft through the application of slow-releasing film with FK506/ NGF/ RGD composites

复合FK506/NGF/RGD缓释膜应用于同种异体神经移植的实验研究

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Construction of Fusion Gene Coding for RGD Peptide and Urokinase B Chain and Its Expression in Escherichia Coli and Characterization 2.The Study on Suppression of Metastatic Potential of Cancer Cells with Urokinase Amino-terminal Fragment Gene Tran

RGD肽与尿激酶B链融合蛋白表达载体的构建、表达及生物活性的初步分析2、尿激酶氨基末端基因转染抗肿瘤转移的实验研究

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By applying of genetic engineering strategies a Bombyx mori silk fibroin-RGD fusion protein ( Silk-RGD) was synthesize, which showed a high cell adhesive ability, and the technological conditions for salting-out purification of the Silk-RGD were studied.

利用基因重组技术合成了具有良好细胞粘附活性的重组家蚕丝素-RGD融合蛋白质(Silk-RGD),探讨了其盐析的工艺条件。

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RGD-containing peptides have been reported to inhibit tumor metastasis, tumor-induced angiogenesis and tumor-elicited platelet aggregations.

据报道,含有RGD的肽具有抑制肿瘤细胞粘附、抗癌细胞转移和 抗肿瘤 新血管生成等方面的功能.

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Researchers have devised replacement platelets, such as red blood cells outfitted with a three-amino-acid sequence called RGD that natural platelets latch on to, thus potentially inducing a clot.

研究人员设计出了血小板替代品,例如:有一种红细胞,带有三种氨基酸的序列,这种序列被称为RGD,是天然血小板的依附之处,因此可能会导致血液凝结。

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Objective To investigate the effects of Tye Ile Gly Ser Arg ( YIGSR) and Arg Gly Asp ( RGD) polypeptides on the fenestrae of the liver sinusoidal endothelial cells ( SECs).

目的探讨酪氨酸-异亮氨酸-甘氨酸-丝氨酸-精氨酸(Tyr-Ile-Gly-Ser-Arg,YIGSR)五肽及精氨酸-甘氨酸-天门冬氨酸(Arg-Gly-Asp,RGD)三肽对肝窦内皮细胞(SEC)窗孔的影响。

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Biological Synthesis and Purification of Spider Dragline Silk Protein Polymers Containing RGD Three Peptide

RGD-蜘蛛拖丝蛋白聚合物的生物合成与纯化

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The Biosynthesis of Spider Dragline Silk Protein Containing the RGD Motif and Preparation of Silk Film; Some spiders mimic insects such as ants.

RGD-蛛丝蛋白生物合成与丝膜制备有些蜘蛛摹拟成如蚂蚁一类的昆虫的样子。

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the role of yigsr and rgd peptides in regulating fenestrae of sinusoidal endothelial cells

五肽及三肽对肝窦内皮细胞窗孔调节的扫描电镜观察

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therefore, the characteristic tripeptide sequence arg-gly-asp (rgd) has been attracting much attention of investigators.

因此,关于这个特有的RGD三肽序列的研究吸引了许多的学者的关注。

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preparation and characterization of liposome of rgd tripeptide as cell recognition site

细胞粘附位点RGD三肽脂质体的制备及表征

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effects of rgd tripeptide on the expression of fak and ha in glomerular mesangial cells

精甘天三肽对肾小球系膜细胞FAK及HA表达的影响

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rgd can affect the aggregation of the infected rtc, indicating its potential therapeutic values.

RGD能够影响受HFRSV感染后RTC的聚集状态,提示了RGD在肾综合征出血热ARF中的潜在治疗作用。

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RGD is composed of three amino acids, arginine ( Arg ), glycine ( Gly ) and aspartic acid ( Asp ).

RGD是 由精氨酸 ( Arg ) 、 甘氨酸 ( Gly ) 、天冬氨酸 ( Asp ) 三个氨基酸组成的序列肽, 是近几年来发现的具有生物活性的短肽序列之一.

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Takintg L-Arginine, L-Glycine and L-Aspartate as a raw material, used DCC coupling method to synthesize Arg-Gly-Asp ( RGD ).

以L - 精氨酸 、 L - 甘氨酸、L - 天门氨酸为原料, 采用二环己基碳二亚胺(DCC)法合成了Arg-Gly-Asp ( RGD ).

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Arg Gly Asp ( RGD ) is one of the oligopeptides with biological activity found in recent years.

精氨酰-甘氨酰-天冬氨酸 ( RGD ) 是具有生物活性的短肽序列之一.

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Solid-state Structure of Bombyx mori Silk Fibroin-RGD Fusion Proteins and Their Cell Adhesive Ability

桑蚕丝素-RGD融合蛋白的固态结构及其细胞粘附性分析

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