1、

However, plasmid-based gene transfer has been accompanied by remarkable biologic effects when used to mediate in vivo expression of potent secreted molecule, such as VEGF, so that the effects of gene transfer would be amplified effectively by a paracrine mechanism.

然而,质粒介导的转基因,如基因产物在体内是高效能的细胞分泌分子,如VEGF,可取得明显的生物学效应,主要因为基因转染的效能被细胞旁分泌作用扩大。

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The most prevalent subtypes are multiple polymyositis ( PM), dermatomyositis ( DM) and inclusion body myositis ( IBM). The adenosine is the signaling molecule of autocrine or paracrine pathway, and plays an important role in maintaining the internal environment stability.

以多发性肌炎(PM)、皮肌炎(DM)和包涵体肌炎(IBM)3个亚型最为多见。腺苷是细胞自分泌或旁分泌途径中的信号分子,在维持内环境稳定方面起重要作用。

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3、

a variety of ovarian autocrine and paracrine factors may modulate folliculogenesis and steroid production.

各种卵巢自分泌和旁分泌的因素可能与激素调节卵泡生产。

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furthermore, the endocrine cells in the mucosa of the body of the stomach also had a paracrine effect on the adjacent cells.

胃体部内分泌细胞除以经典内分泌方式释放激素外,也可以旁分泌方式对周围细胞产生影响。

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stem cells: a paracrine effect in heart failure?

干细胞:心力衰竭时通过旁分泌发挥作用?

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some studies have demonstrated that vegf have not only paracrine effect upon the endothelial cell to promote angiogenesis, also an autocrine effect upon the tumor cell receptor itself.

研究表明,VEGF不仅以旁分泌的形式促进肿瘤血管的生成,也可能通过自分泌形式作用于肿瘤细胞自身的VEGF受体而促进肿瘤细胞生长。

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the paracrine effect of phenytoin on the post-infarct healing process and gene expression profiles after experimental myocardial infarction

苯妥英钠中介的旁分泌作用对心肌梗死后组织修复的影响及相关表达谱芯片研究

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improved functions of hepatocytes may be influenced by msc cells' paracrine effect and suppression of function associated phosphorylation pathways.

肝细胞功能的提高可能与间充质干细胞的旁分泌效应以及多条功能相关的磷酸化通路受到抑制有关。

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The studies found that EPCs can osteogenic differentiation, and enhance the ability of self-healing and the formation of blood vessels in ischemic tissue through paracrine potential for treatment of ANFH.

研究发现EPCs具有可以向成骨方向分化,通过旁分泌作用增强缺血组织自我修复和形成血管的能力,有用于治疗ANFH的潜力。

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G cells may possess endocrine, paracrine and exocrine functions simultaneously.

G细胞可能同时具备内分泌 、 旁分泌和外分泌方式.

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11、

Cytokines can affect the biological characters of melanocytes through autocrine or paracrine modes of action.

细胞因子通过自分泌或旁分泌的方式影响黑素细胞的生物学特性.

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Three categories of cell communication signals are introduced: autocrine , paracrine, and endocrine.

三细胞通信信号类别介绍: 自分泌, 旁分泌和内分泌.

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This is realized by part of paracrine and autocrine controlling follicular function through the differentiation of follicular cells, activity of aromatizing enzyme and level of cAMP.

这种作用体现在局部的旁分泌和自分泌,通过影响卵泡细胞的分化、芳香化酶的活性和cAMP水平等实现对卵泡机能的调节。

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Conclusion In the myocardial hypertrophy models, cardiac ADM increased may due to its local anti-function on myocardial hypertrophy as an autocrine and ( or) paracrine hormone combined with ANP.

结论在心肌肥厚模型中,心肌ADM升高可能是作为心肌自分泌和/或旁分泌激素在局部起抗心肌肥厚的作用,ADM和ANP可能组成抗肥厚的调节组合。

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Key paracrine interactions between glioma cells and the brain microenvironment can influence glioma pathobiology and therefore contribute to its poor prognosis.

本文讨论了目前对于通过影响肿瘤细胞和正常细胞的旁分泌作用治疗胶质瘤的方法。

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Whether local autocrine and paracrine factors within target organs such as the heart modulate AMPK is unknown.

现尚未清楚是否是由心脏等靶器官内的局部自分泌和旁分泌因子调控AMPK。

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Conclusion: It was suggested that MMP-2 expression is increased by paracrine stimulation mediated by soluble factors originated from oral CAFs and MMP-9 expression requires direct cell-cell contact.

结论:MMP-2表达增加可能受到源自口腔癌相关成纤维细胞可溶性因子的旁分泌介导,而MMP-9表达可能需要口腔癌细胞与癌相关成纤维细胞的直接接触。

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