1、

The pathological changes of brain, such as neurofibrillary tangle ( NFT) and senile plaque ( SP), were observed by using HE staining and Bielschowsky staining.

苏木精-伊红染色观察神经细胞形态和数量,Bielschowsky染色观察神经元纤维缠结(NFT)和老年斑等病理改变。

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2、

Toxications of the central nerve system include impairment of learning and memory, neurofibrillary tangles ( NFTs) in different brain tissues, increasingly gathered aluminum in the brain and the functional decrease of the central cholinergic nerve.

其对中枢神经系统的毒性作用可引起学习记忆障碍,引起脑内多种组织出现神经纤维缠结,且脑组织铝含量明显升高,同时脑内胆碱能神经功能明显降低。

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3、

The mainly pathological changes in AD included senile plaque formed with A β deposition, neurofibrillary tangles ( NFTs), synapses loss and neural cell death.

AD的病理变化主要是β淀粉样蛋白(Aβ)沉积造成的老年斑、神经纤维缠结、突触丢失和神经元死亡。

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4、

Neuritic plaques ( NPs) and neurofibrillary tangles ( NFTs) are the two most characteristic pathologic hallmarks of AD.

神经炎性斑块和神经纤维缠结是AD主要的病理学特征。

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5、

The main histopathological hallmarks of AD are extracellular amyloid plaques and intracellular neurofibrillary tangles ( NFTs) in brain cortex, and decrease of brain cortex cells.

AD的特征性病理学改变为大脑皮质神经细胞内神经原纤维缠结、细胞外大量老年斑形成和大脑皮质细胞减少。

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6、

segmentation of senile plaques and neurofibrillary tangles is crucial to pathological analysis of alzheimer's disease.

老年斑和神经元缠结的分割提取对于阿尔茨海默症病理研究有重要的意义。

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7、

role of tau protein in neurofibrillary degeneration of alzheimer disease

tau蛋白在老年性痴呆症神经原纤维退行性变中的作用

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8、

neurofibrillary tangles in als and parkinsonism-dementia complex focus in kii, japan

ALS和帕金森痴呆症中的神经元纤维缠结现象重点在日本纪伊

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9、

Human apoE 4 has been found in senile plaques ( SPs ) and neurofibrillary tangles ( NTFs ) in AD brains.

研究进一步表明,AD患者脑内的老年斑和神经原纤维缠结中存在有较多的载脂蛋白E4 ( apolipoproteinE4, apoE4 ).

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10、

Definitie diagnosis requires postmortem identification of amyloid plaques and neurofibrillary tangles linked to the disease.

最终确诊需要尸检发现与本病相关的淀粉样蛋白斑及神经纤维缠结.

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11、

The characteristic change of pathology in AD were neuritic plaques ( NP), neurofibrillary tangles ( NFTs) and the loss of cholinergic neuron.

主要的病理改变为神经炎斑,神经纤维缠结,胆碱能神经元丢失等。

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12、

In Non-gmo models most only simulate a certain aspect of AD pathology characteristics, while the pathological process of AD is complex, various, and do not present the AD typical characteristic in the brain: senile plaques ( SP) and neurofibrillary tangles ( NFTs).

非转基因模型中,大部分模型只针对AD病理特征的某一个方面,而AD的病理过程是复杂的多方面的,且不呈现AD脑内特征性改变:SP和NFTs。

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