1、

Appearance of some novel proteins binding enhancer element of globin gene ( hs_2) during erythroid terminal differentiation

红细胞终末分化期出现与珠蛋白基因表达增强子HS2序列特异结合的蛋白质因子

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2、

The α-globin gene of yak was amplified and cloned by using the primers based on the conserved region of the upstream from the initiation codon and the downstream from the termination codon.

根据α-珠蛋白基因起始密码子上游及终止密码子下游的保守序列设计引物,以牦牛基因组DNA为模板克隆并测定了α-珠蛋白基因序列。

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3、

Cloning and sequencing analysis of Chinese yak β-globin gene

中国牦牛β-珠蛋白基因的克隆和序列分析

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4、

Additionally, the increase of fetal hemoglobin ( HbF, α_2 γ_2) can ameliorate the clinical symptoms of inherited abnormalities of β-globin gene expression, such as β-thalassemia and sickle cell anemia.

另外,胎儿血红蛋白(HbF,α2γ2)的升高能够减轻由于β-珠蛋白基因表达异常所致的遗传病(如β-地中海贫血和镰刀型细胞贫血)的临床症状。

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5、

Results By PCR-RDB, nine people were proven to have typical phenotypes of β-thalassemia, which were not categorized into the sixteen known genotypes though. The β-globin gene mutations were characterized by PCR-reverse dot blot ( RDB).

结果运用PCR-反向点杂交技术进行基因筛查,发现9例具有典型β-地中海贫血表型特征,但不属于已知的16种β-地中海贫血突变类型。

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6、

The Study of the Mechanisms of γ-globin Gene Reactivation in Non-deletion HPFH and Yunnanese ( A γδβ)~ 0-thalassemia in Transgenic Mice

利用转基因小鼠研究启动子突变HPFH及Yunnanese(Aγδβ)~0-地贫中γ-珠蛋白基因再活化的机制

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7、

However, naturally occurring deletion or point mutations within the β-globin gene cluster may interfere with the fetal-to-adult switching and result in the expression of the y-globin genes persisting at high levels in adults.

然而,天然发生的β-珠蛋白基因簇内的缺失突变或γ-珠蛋白基因启动子点突变可能影响胎儿到成人的开关,导致γ-珠蛋白基因在成人期持续活跃表达。

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8、

Quantitative Analysis of Human Globin Gene Expression in β-thalassemia Using Real-Time RT-PCR

应用实时定量RT-PCR技术检测β地中海贫血珠蛋白基因的表达

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9、

Analysis of mRNA Expression in Human β~ ( 654) Globin Gene Transgenic Mice by Fluorescent Quantitive RT-PCR

荧光定量RT-PCR技术分析人地中海贫血β~(654)珠蛋白基因转基因小鼠mRNA的表达

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10、

The Transcriptional Regulation Study on Human δ Globin Gene with CAAT Box C → T Point Mutation in Its Promoter

人δ珠蛋白基因启动子区CAAT盒C→T突变对其转录的影响

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11、

Reactivation of Fetal Globin Gene in Adult Bone Marrow Erythroid Cells in Culture Conditions

成人骨髓红细胞中胎儿珠蛋白基因在培养条件下重新活化

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12、

Identification of β-globin Gene in Peking Duck's Genomic DNA

北京鸭核DNA中β-珠蛋白基因的初步鉴定

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