conclusion: human leukocyte antigen restriction and cd4 t cell nonresponsiveness as well as the hbeag adjustment of immunological tolerance determine that the turning point of the illness state and cell immune function of chronic hbv carriers occurs at the age around 30 years old.

objective to establish the model of immunological tolerance induced by simultaneous auxiliary liver transplantation and heterotopic heart transplantation using pvg ( tr-1~ c) and da ( rt-1~ a) rats as donors and recipients, respectively.

目的利用PVG（TR-1c）和DA（RT-1a）大鼠分别为供受体，联合进行辅助性肝移植和异位心脏移植，建立大鼠辅助性肝移植诱导免疫耐受模型。

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there are more and more applications in integrating transgenic technology into immunology, especially in molecular immunology, immunological tolerance, autoimmunity, transplantation immunity, anti-infectious immunity, immunoprophylaxis and immunotherapy.

转基因动物技术在分子免疫、免疫耐受、自身免疫、移植免疫、抗感染免疫和免疫防治等研究中的应用日益广泛。

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the mature dc can activate naive t cells to intermediate transplantation rejection. immature dc can induce t cells non-responsiveness to cause the immunological tolerance because of the costimulator molecule expressive defects.

成熟DC可以激活静息T细胞而介导移植排斥；不成熟DC由于共刺激分子表达缺陷，而诱导T细胞的无反应性，导致免疫耐受。

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its gene immunotherapy includes inducing immunological tolerance, changing the functions and activities of antigen presenting cells, modulating immune regulation cytokines, interfering with co-simulating signals and modulating cell apoptosis.

其基因免疫治疗主要包括诱导免疫耐受、改变抗原提呈细胞的功能及活性、改变免疫调节细胞因子、干扰协同刺激信号和调节细胞凋亡。

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it is now recognized that dc can either cause the transplantation rejection, or induce the immunological tolerance, depending on the source of dc, its differentiation and maturity status.

目前认为，DC既可引起移植排斥，也可诱导移植耐受，这取决于DC的来源及其分化发育状态。

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objective to compare the effects of immunological tolerance induced by administration of allogeneic splenocytes through portal vein ( portal venous tolerance) and intestinal tract ( oral tolerance).

目的：比较异基因脾细胞经受体门静脉和口服两种途径输注诱导免疫耐受的疗效。

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aim: to investigate if the immunological tolerance induced by superantigen staphylococcus enterotoxin b ( seb) takes part in the reaction at the immune privileged site.

目的：探讨超抗原葡萄球菌肠毒素B（SEB）诱导的耐受性是否参与免疫赦免部位的应答反应。

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at present, the immunological tolerance in transplantation induced by multi-mechanisms, to inhibit the chronic graft rejection, represents an important trend in the field of transplantation.

目前，移植领域的一个重要方向就是诱导多机制起作用的免疫耐受，防治人体对同种异体器官的慢性排斥反应。

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conclusion: the pretreatment of herba asari lignin combined with donor spleen cells can significantly induce immunological tolerance on the cardiac allograft survival of rats.

结论：细辛木脂素能够明显提高供体脾细胞所诱导的免疫耐受强度，显著地延长大鼠同种异移植体心脏的存活时间。

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objective: to study the effects of immunological tolerance induced by administration of allogeneic splenocytes through portal vein in rats in combination with daclizumab.

目的：观察异基因脾细胞经门静脉途径输注诱导受体免疫耐受的效果，以及联合使用塞尼哌后的效果。

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therapeutic vaccine, which can break up immunological tolerance and stimulate specific immune response, is an efficient new technique on treatment of chronic infection disease and tumor.

治疗性疫苗是指能打破慢性感染者体内免疫耐受、重建免疫应答的新型疫苗，以诱导细胞免疫应答为主，是抗病毒、抗肿瘤治疗新手段。

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conclusion the donor specific antigens can induce the donor specific immunological tolerance. it may be a practicable approach for the clinical experiments in the future.

结论供者特异性抗原能诱导受体免疫耐受并促进移植物存活，可望成为较理想的临床免疫耐受诱导方法。

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the american immunologist forrest provoked the negative selection algorithm based on the sns model and successfully simulated the procedure of immunological tolerance.

美国免疫学教授Forrest基于SNS模型提出了否定选择算法，成功的模拟了免疫耐受的过程。

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established the model by transfused tolerogenic dendritic cells in abdominal cavity to induce immunological tolerance in the mouse

腹腔输注耐受性树突状细胞诱导小鼠免疫耐受研究

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conclusion allogeneic umbilical blood infusion can induce immunological tolerance in the recipients in newborn pigs.

结论新生猪同种异基因脐血输注能诱导受者对供者产生免疫耐受。

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experimental study on immunological tolerance for xeno-skin grafting induced by chimeric donors

嵌合体供者诱导异种皮肤移植免疫耐受的研究

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dendritic cells induce immunological tolerance after organ transplantation

树突状细胞诱导的器官移植后免疫耐受

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the effects of immunological tolerance induced by administration of allogeneic splenocytes in rats

输注异基因脾细胞诱导大鼠免疫耐受的实验研究

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this study can provide the experimental basis to develop the study on allogeneic corneal transplantation immunological tolerance.

为开展同－种异体角膜移植免疫耐受的研究提供实验依据。

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study of the immunological tolerance induced by peripheral intravenous infusion of donor specific antigens

供者特异性抗原经外周输注诱导免疫耐受的研究

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