it is already clear that "the next best thing to being there" is going to be a picturephone call.

don't tell me you can't see where you've painted over the frame and onto the window, it's as plain as a pikestaff.

不要告诉我你不知道你把油漆刷过了架子，而刷到了窗户上，那不是明摆着的么。

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he's as plain as a pikestaff, poor boy, and keenly aware of it.

可怜的孩子，他相貌平平，而且有自知之明。

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medieval weapon consisting of a spearhead attached to a long pole or pikestaff; superseded by the bayonet.

中世纪的武器，有尖锋附在长杆或枪柄上，后在被刺刀取代。

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if you were just to address that letter to joe bloggs, it would almost certainly never arrive.

如果你只在地址栏写下他的名字，那信极有可能永远无法到达。

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some theoretical problems concerning authors'meatal right

有关作者精神权利的几个理论问题

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objective: to investigate the surgical treatment of meatal adenoid cystic carcinoma.

目的：研究外耳道囊性腺样癌的临床手术治疗。

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the application and development of this technique in tuition meatal analysis up_to_date are reviewed respectiuely.

本文对其在环境分析中应用及最新进展进行评述。

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the study of pancreatic stellate cell in the mechanism of pancreatic fibrosis and intervention of salvianolic acid b

胰腺星状细胞在胰腺纤维化中的作用及丹酚酸B的干预阻断研究

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light microscope evaluation: there was no significant fibrosis in pancreas tissue in control group.

结果：1.光镜下：对照组胰腺组织未见明显纤维化。

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extracellular signals, such as growth factors, peptide hormones and neurotransmitters, activate erk cascades to execute complex cellular programs, like proliferation, differentiation and apoptosis, which involved in the fibrogenesis of many organs, such as liver, kidney, lung and pancreas.

其中，ERK通路主要被生长因子、多肽类激素以及神经递质激活，控制着细胞增殖、分化、生存和凋亡，与多种脏器，例如肝脏、肾脏、肺以及胰腺的纤维化密切相关。

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effect of pentoxifylline on pancreas fibrosis in rat

己酮可可碱对大鼠胰腺纤维化的影响

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regulation of angiotensin ⅱ on cell apoptosis during the development of rat pancreatic fibrosis

血管紧张素Ⅱ对大鼠胰腺纤维化过程中细胞凋亡的调节作用

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inhibition of pancreatic fibrosis by angiotensin ii type i receptor antagonist in rats

1型血管紧张素Ⅱ受体拮抗剂抑制大鼠胰腺纤维化形成

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a mechanism study of sophorcarpidine in treatment of pancreatic fibrosis

苦参碱抗大鼠胰腺纤维化作用及机制研究

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expression of angiotensin ii receptors after pancreatic fibrosis in rats

血管紧张素Ⅱ受体在胰腺纤维化大鼠胰腺组织中的表达及其意义

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increasing evidences suggest that oxidative stress and lipid peroxidation have tight relation with pancreatic fibrosis. they not only induce pancreatic cell damage directly, but also can activate pscs, so promote the fibrotic process.

越来越多的研究显示胰腺纤维化的发生发展与氧化应激、脂质过氧化等有关：氧化应激不仅能够直接导致胰腺细胞损伤，还能激活PSCs，加速纤维化进程。

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in conclusion, oxidative stress, activation of pscs and cytokines are the important mechanisms of pancreatic fibrosis and they interact.

氧化应激、PSCs活化和细胞因子是胰腺纤维化的重要机制，三者之间存在交互作用。

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conclusions losartan alleviates tnbs-induced pancreatic fibrosis in rats, suggesting that rennin-angiotensin system might be one of the important contributors for formation of pancreatic fibrosis.

结论1型血管紧张素Ⅱ受体拮抗剂对TNBS诱导的大鼠胰腺纤维化形成具有抑制作用，表明肾素血管紧张素系统（RAS）在慢性胰腺炎胰腺纤维化的发生发展过程中起重要的介导调节作用。

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progressive fibrosis is a characteristic feature of chronic pancreatitis, and pancreatic stellate cell plays an important role in the fibrotic progression of pancreas.

胰腺纤维化是各类慢性胰腺炎的共同特征，胰腺星状细胞（PSC）在胰腺纤维化进程中起重要作用。

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pancreatic fibrosis was induced by intraperitoneal injection with diethyldithiocarbamate ( ddc 750 mg/ kg body weight) in rats.

以腹腔注射DDC（750mg/kg体重）每周2次，共6周建立胰腺纤维化动物模型，治疗组于DDC注射后2周起每日腹腔注射苦参碱（100mg/kg体重），6周后处死动物。

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