OBJECTIVE To determine the serum levels of doxycycline hyclate modified-release pellets after oral administration and to evaluate in vivo and in vitro correlation by deconvolution method.

1、

The doxycycline hydrochloride capsules treatment group had no obvious side-effects Conclusion: The doxycycline hydrochloride capsules treatment on acne vulgaris is satisfaction, lack side-effect

结论：盐酸多西环素胶囊治疗寻常痤疮有效，副作用少

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Mice in treatment group were injected with doxycycline and mice in control group with physiological saline solution everday when tumor could be touched.

待小鼠出现可触及肿块后开始给药，给药组每日腹腔注射盐酸多西环素，对照组给予等量生理盐水。

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3、

An ultraviolet spectrophotometry was established to determine the tylosin tartrate and doxycycline hyclate content in the tylosin tartrate and doxycycline hyclate soluble powder.

建立了双波长紫外分光光度法同时测定酒石酸泰乐菌素-盐酸多西环素可溶性粉中酒石酸泰乐菌素和盐酸多西环素含量的检测方法。

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4、

Objective To compare the absorption efficacy of doxycycline hyclate between gingival injection of gel delivery system and oral administration of the tablets.

目的比较盐酸多西环素注入用缓释凝胶局部牙龈给药与口服给药的优劣。

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5、

Preparation of doxycycline hyclate modified-release pellets AIM: To study the bioequivalence and pharmacokinetics of doxycycline enteric-coated microsomes capsules and doxycycline tablets.

盐酸多西环素调释微丸的制备及处方因素考察目的：研究多西环素肠溶微粒胶囊和多西环素片的人体生物等效性与药动学。

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6、

Objective: The aim of study was to investigate the effects and side-effects of doxycycline hydrochloride capsules treatment on acne vulgaris;

目的：为评价盐酸多西环素胶囊治疗寻常痤疮的疗效及不良反应；

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7、

A dual-wavelength ultraviolet spectrophotometry for determination of enrofloxacin and doxycycline hyclate in compound enrofloxacin soluble powder is established.

建立了复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素含量的检测方法。采用双波长紫外分光光度法，直接测定两组分的含量。

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8、

Study on Compound Danshen Pulse Time-controlled Release Tablet Preparation and Its Release Characteristics in Vitro and in Vivo

复方丹参脉冲控释片的制备工艺及体内外释药特性的研究盐酸多西环素调释胶囊释放度与体内血药浓度相关性考察

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9、

A randomized controlled study of clinical efficacy and safety on domestic doxycycline injection in treating bacterial infections

注射用盐酸多西环素随机对照治疗细菌性感染的疗效与安全性

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Release of doxycycline hydrochloride from hydroxyapatite microspheres

盐酸多西环素羟基磷灰石微球的药物释放

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11、

The doxycycline hydrochloride and its preparations were determinated by first derivative differential pulse polarography.

建立了盐酸多西环素及制剂的一阶导数差示脉冲极谱测定法。

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12、

Pharmacokinetics of a single dose of Doxycycline hydrochloride for injection in healthy Chinese male

中国男性健康志愿者单剂量用盐酸多西环素的药代动力学研究

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13、

Procedure-Proceed as directed for Procedure in the Assay under Doxycycline Hyclate.

步骤：按盐酸多西环素的含量测定项下进行。

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Preparation and Evaluation of Doxycycline Hydrochloride Liposomes Gel

盐酸多西环素脂质体凝胶剂的制备与评价

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15、

Clinical observation of acne vulgaris treated with doxycycline hydrochloride capsules

盐酸多西环素胶囊治疗寻常痤疮的临床观察

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16、

Conclusion Doxycycline hydrochloride is an effective drug in treating acne.

结论盐酸多西环素是治疗痤疮的有效药物。

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17、

Objective: To observe the effects of doxycycline on matrix metalloproteinases-9 ( MMP-9) and ventricular remodeling ( VRM) in rats after myocardial infarction and discuss its mechanisms.

目的：观察盐酸多西环素对心肌梗死后心肌基质金属蛋白酶-9（MMP-9）的影响及对心室重构的作用机制。

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18、

Determination Content of Doxycycline Hyclate Powder by HPLC

HPLC测定盐酸多西环素可溶性粉含量

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19、

Conclusion The serum concentration-time curve of doxycycline hydrochloride fit two-compartment model. The pharmaceutical characteristics of doxycycline hydrochloride in human body were linear in the range of 100mg~ 300mg.

结论9名健康受试者分别静脉滴注盐酸多西环素，药-时曲线符合二房室模型，在100～300mg剂量范围内药物体内过程呈线性动力学特征。

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20、

Methods: 60 cases of acne vulgaris were randomly divided into two groups: Group A ( 30 cases) were treated with doxycycline hydrochloride capsules for three weeks; Group B were treated with minocycline capsules for three weeks;

方法：对60例寻常痤疮随机分为二组治疗，A组（30例）用盐酸多西环素胶囊治疗，B组（30例）用二甲胺四环素胶囊治疗，治疗时间均为21天；

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