Preparation of doxycycline hyclate modified-release pellets AIM: To study the bioequivalence and pharmacokinetics of doxycycline enteric-coated microsomes capsules and doxycycline tablets.

1、

Objective: The aim of study was to investigate the effects and side-effects of doxycycline hydrochloride capsules treatment on acne vulgaris;

目的：为评价盐酸多西环素胶囊治疗寻常痤疮的疗效及不良反应；

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A dual-wavelength ultraviolet spectrophotometry for determination of enrofloxacin and doxycycline hyclate in compound enrofloxacin soluble powder is established.

建立了复方恩诺沙星可溶性粉中恩诺沙星和盐酸多西环素含量的检测方法。采用双波长紫外分光光度法，直接测定两组分的含量。

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Study on Compound Danshen Pulse Time-controlled Release Tablet Preparation and Its Release Characteristics in Vitro and in Vivo

复方丹参脉冲控释片的制备工艺及体内外释药特性的研究盐酸多西环素调释胶囊释放度与体内血药浓度相关性考察

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A randomized controlled study of clinical efficacy and safety on domestic doxycycline injection in treating bacterial infections

注射用盐酸多西环素随机对照治疗细菌性感染的疗效与安全性

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Release of doxycycline hydrochloride from hydroxyapatite microspheres

盐酸多西环素羟基磷灰石微球的药物释放

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The doxycycline hydrochloride and its preparations were determinated by first derivative differential pulse polarography.

建立了盐酸多西环素及制剂的一阶导数差示脉冲极谱测定法。

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Pharmacokinetics of a single dose of Doxycycline hydrochloride for injection in healthy Chinese male

中国男性健康志愿者单剂量用盐酸多西环素的药代动力学研究

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Procedure-Proceed as directed for Procedure in the Assay under Doxycycline Hyclate.

步骤：按盐酸多西环素的含量测定项下进行。

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Preparation and Evaluation of Doxycycline Hydrochloride Liposomes Gel

盐酸多西环素脂质体凝胶剂的制备与评价

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Clinical observation of acne vulgaris treated with doxycycline hydrochloride capsules

盐酸多西环素胶囊治疗寻常痤疮的临床观察

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Conclusion Doxycycline hydrochloride is an effective drug in treating acne.

结论盐酸多西环素是治疗痤疮的有效药物。

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Objective: To observe the effects of doxycycline on matrix metalloproteinases-9 ( MMP-9) and ventricular remodeling ( VRM) in rats after myocardial infarction and discuss its mechanisms.

目的：观察盐酸多西环素对心肌梗死后心肌基质金属蛋白酶-9（MMP-9）的影响及对心室重构的作用机制。

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Determination Content of Doxycycline Hyclate Powder by HPLC

HPLC测定盐酸多西环素可溶性粉含量

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Conclusion The serum concentration-time curve of doxycycline hydrochloride fit two-compartment model. The pharmaceutical characteristics of doxycycline hydrochloride in human body were linear in the range of 100mg~ 300mg.

结论9名健康受试者分别静脉滴注盐酸多西环素，药-时曲线符合二房室模型，在100～300mg剂量范围内药物体内过程呈线性动力学特征。

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Methods: 60 cases of acne vulgaris were randomly divided into two groups: Group A ( 30 cases) were treated with doxycycline hydrochloride capsules for three weeks; Group B were treated with minocycline capsules for three weeks;

方法：对60例寻常痤疮随机分为二组治疗，A组（30例）用盐酸多西环素胶囊治疗，B组（30例）用二甲胺四环素胶囊治疗，治疗时间均为21天；

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Research on the new resistance mechanism of quinolones mediated by aac ( 6')-Ib-cr

aac（6'）-Ib-cr介导的喹喏酮类新耐药机制研究进展

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In order to provide the basic data for using primaquine in vivax malaria control, glucose 6-phosphate dehydrogenase ( G-6-PD) deficiency was investigated in six counties, Hubei Province.

在湖北省6个县市抽样调查人群葡萄糖－6－磷酸脱氢酶（G－6－PD）缺乏情况，以便为疟防工作使用伯喹提供资料。

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Conclusions Imiquimod could induce the pro-inflammatory cytokine secretion and promote the acquired immunity in BALB/ c mice.

结论咪喹莫特诱导BALB/c小鼠分泌IFN-α、IL-12等前炎症因子，并由此促进机体获得性免疫。

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Synthesis and Antibacterial Activity of Pyrazoline and Its Derivatives Progress on Synthesis of 2,3-Disubstituted-4 ( 3H)-quinazolinone Derivatives

吡唑啉及其衍生物的合成与抗菌活性研究2,3-二取代-4（3H）-喹唑啉酮衍生物的合成研究进展

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Effect of artesunate on malarial parasites in mice Result: Both co_naphthoquine and artemisinine could decrease the parasitemia rapidly, but none of them influenced the DNA content of the malarial parasites significantly.

结果：复方磷酸萘酚喹和青蒿素均可以使原虫寄生率迅速下降，但两者对原虫DNA含量的影响均不明显。

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