bcpt

BCPT could increase body weight, sweet water wastage and the crossing scores and rearing scores of the depression model rats.

与模型组大鼠相比，BCPT组大鼠体重增长略有提高，糖水消耗量明显增加，水平活动和垂直活动均明显增加。

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Once administration of 100 mg/ kg BCPT had certain inhibition effect on MAO-A in brain tissues of mice, while 4 hours after administration with BCPT, the inhibition ratio of MAO-A was 66.7%.

拟青霉代谢物提取物100mg/kg1次性给药对小鼠脑组织单胺氧化酶A具有一定的选择性抑制作用，拟青霉代谢物提取物给药后4h，对小鼠脑组织单胺氧化酶A的抑制率达到66.7%。

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Results BCPT could reverse the blepharoptosis and the akinesia induced by reserpine and increase the number of head-twitches induced by 5-HTP in mice.

结果BCPT可拮抗利血平诱导的小鼠上眼睑下垂及运动不能，并增加5-HTP诱导的小鼠甩头次数。

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CONCLUSION: BCPT can improve the anhedonia condition of rats with depression, which may related with the regulation of immunological function and cell factor levels;

结论：拟青霉代谢物提取物可改善抑郁大鼠快感缺乏，该作用的发挥可能与调节免疫功能和细胞因子水平有关；

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Effect of BCPT on AVP content of hypothalamus and pituitary and AVP mRNA of hypothalamus in chronic stress rats

BCPT对慢性应激抑郁大鼠下丘脑、垂体AVP含量及下丘脑AVP mRNA表达的影响

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Conclusion BCPT produces antidepressant-like effect in drug-induced animal models in mice.

结论BCPT对药物诱导的抑郁小鼠具有一定的抗抑郁作用.

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