aminoglycoside

mutation analysis for mitochondrial dna in a chinese pedigree with maternally inherited aminoglycoside antibiotic-induced deafness

母系遗传氨基糖苷类抗生素致聋家系的线粒体DNA突变分析

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Aminoglycoside antibiotics has occupied fairly large market share, it always used on clinical as anti-infective drugs because of its wild antibacterial spectrum, fine curative effect, stable property and any other advantages.

氨基糖苷类抗生素是目前临床上常用的抗感染药物，由于该类抗生素具有抗菌谱广，疗效好，性质稳定等优势，在市场上占据相当的份额。

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The present invention provides macroporous resin enriching and purifying process for aminoglycoside antibiotics.

本发明提供氨基糖苷类抗生素的大孔吸附树脂富集纯化方法.

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At pH 2.0~ 7.0, trypan blue ( TB) reacted with aminoglycoside antibiotics such as kanamycin sulfate ( KANA) and tobramycin sulfate ( TOB) to form blue ion association complexes.

曲利本蓝（TB）与硫酸卡那霉素（KANA）和硫酸妥布霉素（TOB）等氨基糖苷类抗生素在pH2.0～7.0的条件下反应生成蓝色离子缔合物。

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Methods 16 MRSA and 24 MSSA strains were used in this study. The aminoglycoside resistant genes were detected by PCR and aminoglycoside resistance was tested by Kirby-Bauer method to 4 kind of antibiotics ( Amikacin Gentamicin Netilmicin Tobramycin).

方法运用K-B法和PCR方法分别对16株MRSA和24株MSSA4种氨基糖苷药物（丁胺卡那霉素、奈替米星、庆大霉素、妥布霉素）耐药性和氨基糖苷类耐药基因进行检测。

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Conclusion Aminoglycoside modifying enzymes are major factors which confer aminoglycoside resistance on Escherichia coli.

结论产生氨基糖苷类钝化酶是临床分离的大肠埃希菌对氨基糖苷类抗生素主要的耐药机制。

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composition of the goods, other pyrrolic , aminoglycoside and corticosteroid allergy banned drugs.

对本品组成成分、其他吡咯类、氨基糖苷类及皮质激素类药物过敏者禁用。

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study on the drug resistance-related aminoglycoside genes from multi-resistant klebsiella pneumoniae

多重耐药肺炎克雷伯菌氨基糖苷类药物耐药相关基因研究

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Detection of Aminoglycoside-resistance and the Presence of Resistant Genes between MRSA and MSSA

MRSA和MSSA氨基糖苷类药物耐药性和耐药基因检测

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OBJECTIVE To investigate mechanisms of aminoglycoside resistance in pan-drug resistant Pseudomonas aeruginosa ( PDRPA ).

目的探讨泛耐药铜绿假单胞菌 ( PDRPA ) 氨基糖苷类耐药机制.

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From our results , mitochondrial DNA mutation may be one of major factors aminoglycoside antibiotic induced deafness.

提示线粒体DNA点突变是导致该家系致聋的主要因素之一.

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At present, the major topical treatment to eye infection in our country is quinolone eyedrop represented by ofloxacin and ciprofloxacin, and aminoglycoside eyedrop represented by tobramycin.

目前国内在眼部感染的局部治疗方面主要使用氧氟沙星、环丙沙星为代表的喹喏酮类滴眼液和以妥布霉素为代表的氨基糖甙类滴眼液。

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Objective: The experiment was designed to research the relationship between mitochondrial DNA ( mtDNA) mutation and aminoglycoside antibiotic induced deafness ( AAID) and establish a gene diagnostic method.

目的：研究线粒体DNA突变与氨基糖甙类抗生素致聋（AAID）的关系，建立相应的基因诊断方法。

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Conclusion The inheritance mode of AAID is mitochondrial inheritance. Aminoglycoside antibiotic therapy should be avoided in those persons with a family history of AAID, especially their maternal relatives.

结论AAID属线粒体遗传，对具有AAID家族史的个体（尤其是母系亲属），应当避免使用氨基甙类抗生素。

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A Spectrophotometric Study on the Interaction of Aminoglycoside Antibiotics with Titan Yellow and Their Analytical Applications

达旦黄与氨基糖苷类抗生素相互作用的分光光度研究及其分析应用

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OBJECTIVE To investigate molecular epidemiology on aminoglycoside modifying enzyme gene of Pseudomonas aeruginosa.

目的研究铜绿假单胞菌氨基糖苷类修饰酶基因分子流行病学.

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Method Introducing aminoglycoside antibiotic resistant mutation into a pyrrolnitrin producer to increase pyrrolnitrin productivity.

方法在硝吡咯假单胞菌中引入氨基糖苷类抗生素抗性突变,以提高硝吡咯菌素的生产能力.

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methods the mutation of mitochondrial dna from all 18 family members of a chinese pedigree with maternally inherited aminoglycoside antibiotic-induced deafness was detected by pcr and dna sequencing.

方法应用PCR和DNA序列分析技术，对一个有明确氨基糖苷类抗生素应用史的母系遗传耳聋家系共18人（包括聋人和听力正常者）的线粒体DNA进行研究。

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objective: to understand the existence of genes encoding aminoglycoside modifying enzyme in multi-resistant klebsiella pneumoniae.

目的：了解多重耐药肺炎克雷伯菌氨基糖苷类修饰酶基因的存在状况。

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Conclusion Introducing aminoglycoside antibiotic resistance mutation is effective in improving pyrrolnitrin productivity.

结论引入氨基糖苷类抗生素抗性突变,可以有效提高硝吡咯菌的生产能力.

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Aminoglycoside: such as streptomycin, gentamicin, mycophenolate cards, etc.-that.

氨基糖苷类: 如链霉素 、 庆大霉素 、 霉卡那素等.

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B was identified as aminoglycoside compound by general analysis method.

常规的理化分析得出B组分为氨基糖苷类化合物。

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Aminoglycoside antibiotics ( AmAn) are effective drugs in therapy against gram-negative infections, but the ototoxicity and nephrotoxicity limit their use in clinic.

氨基甙类抗生素（AmAn）是一类有效抗革兰阴性菌抗生素，但由于耳毒性和肾毒性，临床应用受到限制。

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Study on the spectrophotometric determination of aminoglycoside antibiotics with trypan red

曲利本红分光光度法测定氨基糖苷类抗生素

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OBJECTIVE To investigate the antimicrobial resistance and genotyping of aminoglycoside-modifying enzymes ( AMEs) and β-lactamases ( BLs) in Klebsiella pneumoniae ( KPN) isolated from hospital-acquired infection in Guangzhou.

目的明确广州地区引起医院感染的肺炎克雷伯菌耐药性及氨基糖苷类修饰酶、β内酰胺酶基因存在状况。

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The present invention provides membrane separating and purifying process for aminoglycoside antibiotics.

本发明提供氨基糖苷类抗生素的膜分离纯化方法.

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