Norvasc

The improved partial least squares ( PLS) method was used to analyze the near infrared ( NIR) reflectance spectrum of norvasc in tablets. The contents of amlodipine besylate, which exist in Norvasc medicine, have been accurately nondestructive quantitatively predicted.

本文用改进的偏最小二乘法（PLS）解析Norvasc药片的近红外（NIR）漫反射光谱，实现了对其中的有效成分苯磺酸氨氯地平的精确的非破坏定量分析。

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Nondestructive Quantitative Analysis of Norvasc in Medicine Tablets by PLS-ANN Arithmetic Combined with NIR Spectroscopy

PLS-ANN算法-NIR光谱非破坏性Norvasc药物有效成分的定量分析

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Compared with the results from HPLC, the relative errors ( RE%) of amlodipine besylate were less than 2.53%. The analytical results could be applied to qualitative control of Norvasc in tablets for practical manufacture.

用HPLC法的测定结果作标准，苯磺酸氨氯地平预测值的相对误差RE（%）<2.53%，可以满足Norvasc药片实际生产中的质量控制要求。

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Nondestructive Quantitative Analysis of Norvasc in Tablets by Improved Partial Least Squares-NIR Spectroscopy

改进的PLS-NIR光谱法非破坏定量分析Norvasc药片

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Norvasc Amlodipine Besylate Molecular formula: C26H31ClN2O8S Properties: white or light yellow crystalline powder, odorless, bitter taste, soluble in water, methanol.

络活喜Amlodipine Besylate分子式：C26H31ClN2O8S性质：白色或淡黄色结晶性粉未，无臭、味苦，易溶于水、甲醇。

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