ECGF

AIM: To investigate the effect of capecitabine ( xeloda) by preoperation administration on the microvessel density ( MVD) and expression of thymidine phosphorylase/ platelet-derived endothelial cell growth factor ( TP/ PD-ECGF) in patients with colorectal cancer.

目的：探讨术前希罗达化疗对结直肠癌胸苷磷酸化酶/血小板衍化内皮细胞生长因子（TP/PD-ECGF）表达、肿瘤组织微血管密度（MVD）的影响。

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To observe the expression of platelet derived endothelial cell growth factor ( PD ECGF) separately in stroma cells, and in cancer cells, and its relationship to the angiogenesis.

探讨宫颈癌中血小板源内皮细胞生长因子（PD ECGF）表达与新生血管形成的关系。

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Oligomerization and enzyme activity of thymidine phosphorylase/ PD ECGF mutant protein

胸腺磷酸化酶/血小板衍生血管生长因子寡聚体形成与酶活性

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CONCLUSION: Preoperation chemotherapy of xeloda can decrease the activity of TP/ PD-ECGF and inhibit the angiogenesis in colorectal cancer.

结论：希罗达术前化疗能使TP/PD-ECGF活性降低，抑制结直肠癌肿瘤血管生成。

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CONCLUSION The rat serum including high dose herb medicine could have an effect on inhibition of proliferation of endothelial cell induced by vascular ECGF.

结论含高剂量中药的大鼠血清有抑制血管内皮细胞生长因子诱导内皮细胞增殖的作用。

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Preparation of ecgf oral liquid and its therapeutic effect on gastric ulcer and gastritis

内皮细胞生长因子口服液的制备及其对胃溃疡和胃炎的治疗作用

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Conclusion Media of HE SFM BGM contained 5% FBS and ITS,β ECGF can culture purified human retinal capillary endothelial cell. Fibronectin coated dishes and growth factors addition are essential for the culture of endothelial cell.

结论利用5%胎牛血清的人内皮细胞培养基，添加生长因子和胰岛素-转铁蛋白-硒添加物，并用纤维连接蛋白包被培养瓶，能简单有效地培养人视网膜血管内皮细胞。

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Objective To construct the expressive vector of PD ECGF.

目的构建血小板衍化内皮细胞生长因子（PD-ECGF）的原核表达载体。

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Endothelial cell growth supplement ( ECGS) was prepared and β-ECGF has been purified from bovine brain.

从牛脑组织中制备了内皮细胞生长因子粗品（ECGS）和纯品（β-ECGF）。

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METHODS: Immunohistochemical staining of CD34 and TP/ PD-ECGF monoclonal antibodies was performed in 32 colorectal cancer patients with preoperative xeloda chemotherapy and 25 cases without chemotherapy ( served as con-trols), and then the expression of TP/ PD-ECGF and MVD were analyzed.

方法：对32例术前应用希罗达化疗的和25例未做术前化疗的结直肠癌标本，进行TP/PD-ECGF、CD34免疫组织化学标记，检测其TP/PD-ECGF表达及微血管密度MVD。

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It is evident that aFGF, bFGF, EGF or ECGF can enhance the proliferation of the ligament fibroblasts from the knee joint significantly.

EGF和ECGF四种生长因子对兔膝关节韧带成纤维细胞有明显的促增殖作用。

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