DHPR

Methods One hundred patients with unknown motor disturbance and mental retardation were referred to this study. All patients were performed by phenylalanine ( Phe) and BH4 loading test, urinary pterin analysis and dihydropteridine reductase ( DHPR) activity.

方法对100例运动及智能障碍患者进行苯丙氨酸（phenylalanine，Phe）及BH4负荷试验、尿蝶呤谱分析、红细胞二氢蝶啶还原酶测定，并对部分患者进行多巴治疗性诊断；

互联网摘选

These results suggest that the3 fractions of DHPR may be structurally related but catalytically distinguishable.

这些结果告诉我们，不同组分的DHPR在结构上有某种联系但催化效应却有差别。

互联网摘选

Conclusions The DHPR activity determination in red cell from dried blood spot is an effective, reliable and feasible method for diagnosis of DHPR deficiency.

结论干滤纸血片中红细胞DHPR活性测定是DHPR缺乏症有效、可靠且易行的诊断方法。

互联网摘选

Urinary biopterin percentage and DHPR activity were all normal in 41 patients, so they were ruled out BH_ 4 deficiency.

41例尿蝶呤及DHPR活性均正常。

互联网摘选