1、

P53 bound full-length Egr-1 and an Egr-1 mutant with a deletion of the 5' trans-activation region but did not associate with Egr-1 protein lacking an internal segment that included the first two zinc finger domains, suggesting that binding may require the presence of intact zinc finger motifs.

p53结合全长的Egr-1和1个Egr-1缺失5'活化范围的Egr-1突变体,但不能结合1个缺少包含头两个锌指区的内部片断的Egr-1蛋白,说明结合需要完整的锌指基序存在。

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2、

The transcription factor Egr-1 and the lung diseases

转录因子Egr-1及其在肺病变中的研究进展

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3、

However, the lung MPO levels in Egr-1 knockout mice were significantly reduced compared with those in wildtype mice [ ( 168.1 ± 41.7)% vs ( 274.0 ± 98.7%), P < 0.05].

肺组织MPO水平与野生型组相比明显降低[(168.1±41.7)%vs(274.0±98.7)%,P<0.05]。

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4、

Treatment with F_2 before hypoxia and reoxygenation significantly attenuated the cardiomyocytes injury and inhibited the overexpression of Egr-1 after H/ R.

缺氧及复氧前给予F2则能改善H/R所致心肌细胞病理损害,抑制心肌细胞Egr-1的过量表达。

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5、

Overexpression of Egr-1 promotes epithelial-to-mesenchymal transition on renal tubular epithelial cells

早期生长反应因子1过表达促进肾小管上皮细胞转分化

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6、

study on cloning of the egr-1 promoter and its radiation-inducible property

小鼠Egr-1启动子的克隆及其辐射诱导特性的研究

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7、

Egr-1 expression had relatively high level in active growth cells.

组织中生长活跃的细胞可见相对高水平的Egr - 1表达.

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