1、

The Effect of Glibenclamide on the K~+-ATP Channels of Pancreatic β TC3 with the Pretreatment of Amylin

胰淀素对优降糖作用于胰岛βTC3细胞ATP敏感性钾通道的影响

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2、

Biochemical examination indicates that amylin can not only promote bone formation, but also inhabit bone resorption, and the interventional effects of 250 μ g/ kg amylin are the best in ameliorating biochemical indexes in blood and urine and biomechanic functions.

生化检查提示胰淀素不仅可以促进骨形成,同时还具有抑制骨吸收的作用,其改善血尿生化指标及骨生物力学性能以250μg/kg胰淀素干预效果最好。

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3、

The turbulence of excretion of amylin induces insulin resistance.

人体内胰淀素分泌的紊乱是诱导胰岛素抵抗发生的原因之一.

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4、

Amylin was mainly distributed in the expanded mesangial area, Kimmelstiel – Wilson nodules, Bowman's capsule, and in blood vessels.

胰淀素主要分布在肾小球系膜基质增多而扩张的系膜区、K-W结节内、肾小球囊和血管上。

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5、

Results: Seventy-two ( 48.3%) of patients have positive staining of amylin in the renal tissue. Amylin was found mainly in the expanded mesangial area, segmental sclerosis, K-W nodules, the Bowman's capsule as well as in blood vessel.

结果72例DN患者(48.3%)肾组织Amylin染色阳性,Amylin主要沉积在肾小球系膜基质增多而扩张的系膜区、K-W结节内、增厚的球囊壁和病变的血管壁。

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6、

Conclusion: Amylin can induce apoptosis of human mesangial cells in vitro.

结论:amylin对人系膜细胞具有细胞毒性作用,并可诱导系膜细胞的凋亡。

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7、

conclusion : low amylin may contribute to theand development of t 2 dm and the change body composition.

结论胰淀素分泌减少可能参与T2DM的发生发展和机体体成分改变.

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