1、

Killing Effect of Human Pulmonary Adenocarcinoma Cells with TK+ CD/ 5-Fc+ GCV Coexpression Suicide Gene Systems

自杀基因CD、TK的共表达对人肺腺癌细胞的杀伤作用

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2、

Two out of six human lung cancer cell lines ( SPCA-1, A549) have a high sensitivity to 5-FC and GCV;

在6种已转染的肺癌细胞株中,有2种肺癌细胞株(SPCA-1,A549)对前体药物5-FC和GCV有较高的敏感性;

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3、

The killing effects of pE-CEA-cd-tk/ 5-FC+ GCV system mediated by cationic liposome targeted to CEA positive lung cancer cells

阳离子脂质体介导pE-CEA-cd-tk对CEA阳性肺癌的杀伤作用

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4、

The most intensively studied strategies involve HSV-tk/ GCV and CD/ 5-Fc systems. But their curative effects also need to be enhanced in order to approach clinical application.

其中HSV-TK/GCV和CD/5-Fc系统是最有应用前景的两种自杀基因系统,但在临床应用上同样面临着需要提高疗效的问题。

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5、

CD/ TK had obvious synergic effects. Ad. CD/ TK combined with GCV and 5-Fc significantly suppressed the growth of nude mice tumor model.

在Bel7402裸鼠移植瘤模型中,联合Ad.CD/TK和GCV、5-Fc能够显著抑制肿瘤的生长。

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6、

In 153 cases of prevention research, 88 were in GCV group and 65 in ACV group;

预防研究共153例,更昔洛韦组88例,阿昔洛韦组65例。

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7、

Suicide gene therapy for glioma using HSV tk/ GCV system

HSV-tk/GCV系统对神经胶质瘤的自杀基因治疗研究

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8、

Use the methods of CV and GCV to estimate nonparametric regression functions

用CV和GCV方法估计非参数回归函数

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9、

The genetic coefficient of variance ( GCV) of seed cotton yield per plant, lint yield per plant, boll number per plant and single boll weight was more than 10%;

相比而言,单株子棉产量、单株皮棉产量、单株铃数、单铃重4个性状的遗传变异潜力较大,遗传变异系数在10%以上;

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10、

Objective To explore the enhanced cell-killing effect in vivo of herpes simplex virus thymidine kinase/ ganciclovir ( HSV-TK/ GCV) gene therapeutic system using tegument viral protein ( VP22) intercellular trafficking.

目的探讨病毒蛋白22(VP22)的细胞间传递作用,以及其促进单纯疱疹病毒胸苷激酶(HSV tK)更昔洛韦(GCV)基因治疗系统对卵巢癌移植瘤细胞的体内杀伤效应。

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11、

The AC of bark decreased as the stand ages increased, the GCV of them changed oppositely.

皮的灰分含量和干重热值随林龄的变化与前者相反。

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12、

At present, the most mature research of suicide gene systems are HSV-TK/ GCV and CD/ 5-FC.

目前研究最为成熟的自杀基因系统是HSV-TK/GCV和CD/5-FC。

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13、

The study on mechanism of enhancing bystander effect of HSV-TK/ GCV system by Rb gene

Rb基因增强HSV-TK/GCV系统旁观者效应的机制研究

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14、

An in Vitro Study on Bystander Effect of the HSV 1 tk/ GCV Gene Therapy System

HSV1tk/GCV基因治疗系统的旁观者效应观察

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15、

The relationship of gap junction with the bystander effect in the HSV-TK/ GCV treatment

细胞缝隙连接与HSV-TK/GCV系统旁观者效应的关系

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16、

Construction of HSV-tk/ GCV suicide gene system for hepatocarcinoma cells and its bystander effect in rats

大鼠肝癌细胞HSV-tk/GCV自杀基因系统的构建及其旁观者效应

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17、

The Enhancing Utility and Mechanism Research of Curcumin on Bystander Effect of HSV-tk/ GCV Suicide Gene System

姜黄素对tk/GCV自杀基因系统旁观者效应的增效作用及机制

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18、

HSVtk/ GCV system-mediated bystander effect on human bladder cancer cells and its potential mechanism

HSVtk/GCV介导的旁观者效应对人膀胱癌的作用机理

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19、

The study of Bystander Effect in RV-HSV-tk-GCV system gene therapy for glioma

RV-HSV-tK-GCV系统基因治疗中的旁观者效应研究

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20、

Objective: To explore the ganciclovir ( GCV) therapy on the severe combined immunodeficiency ( SCID) breast cancer mice after HSVtk gene and Tet On regulatory gene expression induced by doxycycline ( Dox).

目的:探讨经强力霉素(Dox)诱导后,丙氧鸟苷(GCV)对SCID小鼠乳腺癌的调控性治疗作用。

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