CONCLUSION: The results indicated that the solubility and dissolution rate of thiamphenicol were significantly increased when the drug was included by β cyclodextrin.

1、

Simultaneous determination of residues of chloramphenicol, thiamphenicol and florfenicol in aquatic products by gas chromatographic method with electron capture detection

毛细管电子捕获气相色谱法同时测定水产品中氯霉素、甲砜霉素和氟甲砜霉素残留

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METHODS: The inclusion compound of thiamphenicol β cyclodextrins was prepared by the coprecipitation method, and its properties were investigated.

方法：采用共沉淀法制备甲砜霉素的β环糊精包合物，以折光率控制包合工艺，用紫外光谱法及相溶解度图法进行鉴定，并考察其性质。

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The Pharmacokinetic Comparison between Thiamphenicol and HP-β-CD Thiamphenicol in Rabbit

甲砜霉素及HP-β-CD甲砜霉素在家兔体内的药代动力学比较研究

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Determination of Thiamphenicol and Its Tablet by RP-HPLC

RP-HPLC测定甲砜霉素原料及其片剂的含量

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Clinical Observation of Magnesium Sulphate United with Thiamphenicol on Treating Zumbusch Pattern Psoriasis Pustulosa

硫酸镁联合甲砜霉素治疗泛发性脓疱型银屑病的临床疗效观察

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A Gas Chromatography method was developed to simultaneously determine chloramphenicol and thiamphenicol residues in edible tissues of swine.

为检测猪可食用组织中氯霉素和甲砜霉素残留，建立了同时检测这两种残留药物的气相色谱方法。

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Many countries and organizations set down MRLs of chloramphenicol and thiamphenicol in food derived from animals respectively.

所以世界上许多国家和国际组织规定了动物性食品中氯霉素和甲砜霉素的最大残留限量。

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Simultaneous Determination of Chloramphenicol and Thiamphenicol in Fish Tissues by Capillary GC-ECD

同时测定鱼肉中氯霉素和甲砜霉素残留量的毛细管气相色谱法

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Development of Methods for Determination and Confirmation of Chloramphenicol and Thiamphenicol Residues in Food Derived from Animals

动物性食品中氯霉素和甲砜霉素残留的定量及确证方法建立

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CONCLUSION The method is simple, sensitive, accurate and can be used for the determination of Thiamphenicol capsule.

结论所用方法简便、灵敏，结果准确可靠，可用于甲砜霉素胶囊的质量控制。

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Chiral Resolution of Precursor of Chloramphenicol and Thiamphenicol by High Performance Capillary Electrophoresis

氯霉素前体和甲砜霉素前体的毛细管电泳手性分离

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OBJECTIVE To determine the content of Thiamphenicol capsule.

目的建立测定甲砜霉素胶囊含量的方法。

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OBJECTIVE: To improve the solubility and dissolution rate of thiamphenicol.

目的：增加甲砜霉素的溶解度和溶出度，提高药物在体内的生物利用度。

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Based on the data we got, we believed that there should be a third resonant structure of the reaction intermediate hydroxyethyl thiamine pyrophosphate ( HEThDP) besides the reported enamine resonant structure and C2-a-alkenyl carbanion resonant structure, which might be named enol resonant structure.

根据我们得到的数据，我们认为其重要的反应中间体羟乙基硫胺素焦磷酸（HEThDP）除文献报道的烯铵结构和C2α-碳负离子结构之外，还存在第三种共振结构，即烯醇式结构。

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Conclusion The standard of serum thyroxin is important to diagnose hyperthyroidism, we should consult the standard of serum T 3 and TSH when judge the treatment and Thiamazole dose.

结论血清甲状腺素水平是甲亢诊断的重要依据，在判断他巴唑剂量和疗程时应参考血清T3、TSH水平。

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Methods: We made inflammation models with carrageenin and cotton ball implantation to observe its anti-inflammatory action, and with Thiamazole to made thyroid enlargement model.

方法：采用大鼠角叉菜胶性足趾肿胀和棉球植入法致炎症模型，观测药物的抗炎作用；

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The plasma thiamazole level was determined by HPLC after a dose of 20 mg thiamazole orally in 12 male healthy volunteers.

12名男性健康志愿者一次口服20mg甲巯咪唑片后，以HPLC法测定血浆甲巯咪唑浓度，用非房室模型参数估算法计算药物动力学参数。

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Determination of thiamazole ( TMZ) and its tablets by high-speed capillary electrophoresis with amperometric detection

高速毛细管电泳安培法检测甲巯咪唑及其制剂

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Conclusion: This method could be used to determine thiamazole concentrations in patients receiving thiamazole or carbimazole.

结论：本方法适用于服用甲巯咪唑及卡比马唑的临床病人的血药浓度测定，以便进行临床药学研究。

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Review the Effect of Hypothalamus-pituitary Adrenal Hypothyroid and Gonad on Thiamazole Models

对大鼠他巴唑肾阳虚证动物模型下丘脑-垂体-靶腺轴几项指标的考察

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